Changing Epidemiology of Common Cancers in Southern Iran, 2007-2010: A Cross Sectional Study

Abstract

We have evaluated the ever changing epidemiology of cancers in Fars province, Iran since the re-establishment of Fars cancer registry. Based on the collected data from all related sources in Fars province from 2007–2010 we calculated the cancer age-standardized rates per 100,000 person-years (ASRs). The results are presented as incidence rates of cases by site according to the International Classification of Diseases for Oncology (ICD-O), sex, age, crude rate, and ASRs. In women the total ASR was 41.70 per 100,000 from 1985–1989 which had increased to 55.50 and 95.46 during 1998–2002 and 2007–2010. The incidence of breast cancer in women during 2007–2010 was about two and four times higher than 1998–2002 and 1985–1989. The incidence of colorectal cancer in women during 2007–2010 was about three and five times higher than 1998–2002 and 1985–1989. In men the total ASR was 62.9 per 100,000 in 1985–1989 that increased to 64.50 and 101.48 during 1998–2002 and 2007–2010. Although stomach cancer was the most common cancer among men during 1985–1989 and 1998–2002, but in recent study bladder cancer was the most common cancer among men in Fars province. The incidence of colorectal cancer in men during 2007–2010 was about three times higher than 1998–2002 and 1985–1989. This study shows growing incidence of cancer in southern Iran. The colorectal cancer in both genders had increased and its pattern is similar to western countries. In men, bladder and prostate cancers had a growing rate and the incidences of these cancers in the present study were greater than stomach cancer.

Opium Use and Risk of Lower Gastrointestinal Cancers: Population-Based Case-Control Study in South of Iran

“…Also, the annual colon cancer mortality for men and women was 1.54 and 2.46 per 100,000 persons, respectively. Moreover, the mortality rates for colon cancer in the other studies from southern parts of Iran were reported 0.41 and 0.34 per 100,000 persons (1,4,15).…”

“…Colorectal cancer is one of the major cancers in the world (2). Colorectal cancers (including colon, rectum and anus) are the most common type of gastrointestinal tract cancer and allocate the third rank in men and fourth rank in women in Iran (1,3,4). The annual incidence of this cancer is more than 134,000 new cases and 55,000 deaths are reported annually due to colorectal cancer.…”

The Incidence of Esophageal Cancer in Iran: A Systematic Review and Meta-analysis

“…The included studies were published from 1968 to 2017. Based on geographical locations, four studies were conducted in all states of Iran [24][25][26][27], three in Fars province [28][29][30], three in East Azerbaijan [15,31,32], two in Ardabil province [33,34], two in Guilan province [35,36], two in Golestan province [37,38], one in Kerman province [39], one in Semnan province [40], one in Tehran metropolis [41], one in Mazandaran province [42], one in Caspian littoral [43] and one in Shahroud city [44]. All the studies have reported ASRs.…”

“…The low incidence rate of EC in this province can be attributed to the demographic characteristics of people living in this area, differences in lifestyle, and the presence of other types of risk factors and diseases. In Fars province, other types of cancer such as breast, colorectal, and gastric cancers in women and bladder, prostate and gastric cancers in men have higher incidence rates [30,59,60].…”

Permissive/Protective Interplay of Microbiota with T Cell Adaptive Immune Response in Colon Cancer

“…Colon carcinoma is among the leading causes of cancer-related death throughout the world, with a rising incidence rate in recent years (11). Colon is the site where the greatest density and number of microbes can be found.…”