Characteristics of Cognitive Status in Sub-Population of Sub-Acute Stage of Ischemic Stroke Patients in West Nusa Tenggara, Indonesia

Abstract

Cognitive decline is a significant complication that affects most stroke survivors. Early detection of cognitive decline in ischemic stroke patients and identification of risk factors improves their clinical outcomes. This study aimed to determine the characteristics of cognitive status in the sub-acute phase of ischemic stroke. A cross-sectional study was conducted on 89 sub-acute ischemic stroke patients in three hospitals in West Nusa Tenggara recruited consecutively from August 2019 to April 2020. The data collected were demographic and clinical characteristics, cognitive status, and functional outcome. The association between clinical and demographic characteristics and cognitive decline was analyzed using logistic regression. In addition, the relationship between cognitive status and functional outcomes of these patients was examined using the chi-square test. This study revealed that the prevalence of cognitive decline in these subjects was 71.9%. Multiple logistic regression showed that age was the only characteristic associated with cognitive decline in the subjects (OR = 5.12,95% CI = 1.08-24.28). Furthermore, the frequency of cognitive decline in these subjects was significantly associated with functional outcomes (p-value =0.014). Thus, there was a high prevalence of cognitive decline in sub-acute ischemic stroke patients associated with increasing age and poor functional outcomes.

Infarct Diameter for Predicting Cognitive Dysfunction in Ischemic Stroke Survivors in West Nusa Tenggara, Indonesia

“…A previous study investigating the prevalence of post-stroke cognitive dysfunction in the subacute phase showed similar results. 3 In general, the prevalence minant of cognitive dysfunction after ischemic stroke in the patients studied. This result conformed to a study on ischemic stroke patients in Yogyakarta, an urban area in Indonesia with a high human development index.…”

“…Due to the coronavirus 2019 (COVID-19) global pandemic situation, this study was temporarily suspended between defined as fasting blood glucose levels of 126 mg/dL and/or patients taking antidiabetic drugs, as described in previous studies. 3 The presence of atrial fibrillation was determined based on the results of the 12-lead electrocardiography (ECG) examination of the patients reviewed by a cardiologist.…”

“…2 The prevalence is also high in the early phase of stroke (71.9%). 3 The cognitive domains most often affected by stroke are attention, memory, and executive dys function. 4 If not appropriately treated, cognitive dys func tion can progress to dementia after the first few years, characterized by the loss of independence of stroke survivors in carrying out their basic functional and social activities of daily living.…”

Penyuluhan mengenai Gangguan Kognitif Pasca Stroke di Poliklinik Neurologi Rumah Sakit Universitas Mataram

“…Mengingat penyakit stroke saat ini merupakan penyebab kematian dan kecacatan tertinggi di Indonesia, maka kejadian gangguan kognitif pada para pasien stroke dapat diprediksi akan sangat tinggi. Frekuensi gangguan kognitif pasca stroke di Kota Mataram saat ini sebesar 79% dari pasein stroke (Harahap et al 2021). Gangguan kognitif pasca stroke ini umumnya muncul terutama dalam 3 -6 bulan pertama dari waktu awitan stroke dengan spektrum gejala yang bervariasi, mulai dari gangguan kognitif ringan sampai dengan berat.…”