In this chapter, field-effect spin transistors are described from the viewpoint of integrated circuit applications. Firstly, the classification of field-effect spin transistors is described. Then, the MOSFET type of spin transistor, i.e., spin-MOSFET, is focused on, and its device structure, operating principle, performance, and device/process technologies are shown. Pseudo-spin-MOSFET architecture that is a circuit technique for reproducing the functions of spin transistors using an ordinary MOSFET and a magnetic tunnel junction is also described. Finally, technologies, advantages, and issues for energy-efficient logic circuits/systems based on these spin-functional MOSFETs are also addressed.