Characterization of left ventricle energy loss in healthy adults using vector flow mapping: Preliminary results

Xu, Lei; Sun, Chao; Zhu, Xiaoli; Liu, Weihua; Ta, Shengjun; Zhao, Dan; Wang, Feifei; Liu, Liwen

doi:10.1111/echo.13504

Cited by 16 publications

(13 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During isovolumic systole, a large vortex formed around left ventricular outflow tract, which promoted efficient ejection during systole and produced another systolic EL high peak. The abovementioned phenomenon is in consistent with previous observation …”

Section: Discussionmentioning

confidence: 99%

Evaluation of left ventricular diastolic function based on flow energetic parameters in chronic kidney disease with diastolic dysfunction

Wang

Chen

et al. 2019

Echocardiography

View full text Add to dashboard Cite

Background Intra‐ventricular blood flow dynamics is considered as an important component of left ventricular (LV) function assessment. The purpose of this study was to evaluate the LV diastolic function in chronic kidney disease (CKD) with different degrees of LV diastolic dysfunction (LVDD) by using flow energetic parameters. Methods In this study, a total of 96 cases were recruited, including 58 CKD patients and 38 healthy controls. CKD patients were divided into 2 groups according to LVDD severity, named as DD1 and DD2. Vector flow‐mapping (VFM) analysis was executed to calculate left ventricle average energy loss (EL) during early filling phase (E‐EL_ave), atrial filling phase (A‐EL_ave), diastole phase (D‐EL_ave), and ejection phase (S‐EL_ave). Moreover, the average vortex circulation during early filling phase (E‐cir_ave) and atrial filling phase (A‐cir_ave) was also assessed in the apical three‐chamber view. The rate of average EL during early filling and atrial filling was expressed as E/A‐EL. Result Compared to the control group, A‐EL_ave, S‐EL_ave, and A‐cir_ave in the DD1 group were higher (P < 0.05), and all parameters were obviously higher in the DD2 group (P < 0.05). In the control group and the DD2 subgroup, the E‐EL_ave value was significantly higher than A‐EL_ave value, which was opposite to the DD1 group. As diastolic dysfunction worsened, E‐EL_ave and D‐EL_ave risen gradually (P < 0.05), and A‐EL_ave and S‐EL_ave were slightly elevated with no significance. There were significant correlations between LV diastolic function and flow energetic parameters. Stepwise multiple regression analysis revealed that various LV function parameters could be regarded as independent predictors of average diastolic EL (all P < 0.01). Conclusions For CKD patient with LVDD and LVEF > 50%, effective LV filling and systolic ejection with optimized energy consumption have been impaired. As a new flow‐derived index, EL can quantitatively evaluate LV diastolic function in terms of blood fluid dynamics in CKD with various LVDD.

show abstract

Section: Discussionmentioning

confidence: 99%

Evaluation of left ventricular diastolic function based on flow energetic parameters in chronic kidney disease with diastolic dysfunction

Wang

Chen

et al. 2019

Echocardiography

View full text Add to dashboard Cite

show abstract

“…When afterload increases, the contractility of left ventricle increases to ensure a sufficient ejection volume [34]. The increased contraction of left ventricle intensifies the interaction between blood flows, as well as the blood flow and ventricular wall [35], causing more energy dissipation. Moreover, SBP, a clinical indicator representing cardiac afterload, was shown as the predictor of systolic EL in patients with stages 1-3 CKD in present study.…”

Section: Discussionmentioning

confidence: 99%

Assessment of left ventricular energy loss using vector flow mapping in patients with stages 1–3 chronic kidney disease

Chen

Wang

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Background: Patients with chronic kidney disease (CKD) experience abnormality of intracardiac blood flow status during early-stages of disease. Left ventricular energy loss (EL) derived from vector flow mapping (VFM) represents fluid energy lost as heat in left ventricle and had been used to detect intracardiac blood flow efficiency. We aimed to evaluate the left ventricular EL in stage 1-3 CKD patients, and explored whether hypertension, a main cardiovascular risk, deteriorate the abnormality of intracardiac blood flow status. Methods: Transthoracic echocardiography was performed in 41 controls and 48 patients with stages 1-3 CKD. CKD patients consisted a subgroup with no hypertension, a subgroup with well-controlled hypertension and a subgroup with poorly controlled hypertension. The EL were calculated in the left ventricle using VFM analysis from the apical 3-chamber view. Furthermore, the correlation and stepwise multiple regression analysis were used to explore the potential independent predictors of left ventricular EL. Results: Compared with controls, stage 1-3 CKD patients showed increased left ventricular EL during total diastole, late diastole, total systole, isovolumic contraction and ejection. CKD patients with poorly controlled hypertension had higher left ventricular EL compared to the other CKD subgroups. Additionally, the ratio of mitral early filling wave peak velocity and early mitral annular peak velocity on septal side, mitral early filling wave peak velocity, and left ventricular mass index were independent predictors of the diastolic EL; whereas systolic blood pressure and left ventricular mass index were independent predictors of the systolic EL. Conclusions: Left ventricular EL was a useful echocardiographic parameter to evaluate the impaired intracardiac blood flow efficiency in patients with stages 1-3 CKD. Hypertension was a crucial contributor for intracardiac blood flow abnormality. This study might provide valuable clinical data to discern cardiac dysfunction and reduce the cardiovascular risk in early-stage CKD.

show abstract

“…In the VFM analysis in the non‐HCM group, energetically efficient vortices formed in the left ventricle. Those vortices facilitate the inflow into the ventricle, minimize the dissipation of energy, preserve the momentum, and redirect the flow toward the LV outflow 9,23 . In diastole, clockwise and counterclockwise vortices form around the mitral valve.…”

Section: Discussionmentioning

confidence: 99%

Energy loss by right ventricular pacing: Patients with versus without hypertrophic cardiomyopathy

Arakawa

Fukaya

Kakizaki

et al. 2020

Journal of Arrhythmia

View full text Add to dashboard Cite

show abstract

Characterization of left ventricle energy loss in healthy adults using vector flow mapping: Preliminary results

Cited by 16 publications

References 28 publications

Evaluation of left ventricular diastolic function based on flow energetic parameters in chronic kidney disease with diastolic dysfunction

Evaluation of left ventricular diastolic function based on flow energetic parameters in chronic kidney disease with diastolic dysfunction

Assessment of left ventricular energy loss using vector flow mapping in patients with stages 1–3 chronic kidney disease

Energy loss by right ventricular pacing: Patients with versus without hypertrophic cardiomyopathy

Contact Info

Product

Resources

About