1990
DOI: 10.1016/s1042-3680(18)30782-4
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Charged-Particle Radiosurgery of the Brain

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Cited by 42 publications
(51 citation statements)
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“…In the earlier years of the program, patients with vario.us disorders underwent treatment to effect hormonal suppression of disease by induction of hypopituitarism; this included 183 patients with metastatic breast carcinoma and 169 patients with diabetic retinopathy, as well as selected patients with prostatic carcinoma and other adenohypophyseal hormoneresponsive malignancies (Table 1) [6,7,8,9,10,11,12]. In 1958, the charged-particle radiosurgery program was expanded to include patients with endocrine and metabolic disorders of the pituitary gland, i.e., acromegaly, Cushing's disease, Nelson's syndrome, prolactinsecreting adenomas and chromophobe adenomas [8,11,13,14,15,16].…”
Section: Introductionmentioning
confidence: 99%
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“…In the earlier years of the program, patients with vario.us disorders underwent treatment to effect hormonal suppression of disease by induction of hypopituitarism; this included 183 patients with metastatic breast carcinoma and 169 patients with diabetic retinopathy, as well as selected patients with prostatic carcinoma and other adenohypophyseal hormoneresponsive malignancies (Table 1) [6,7,8,9,10,11,12]. In 1958, the charged-particle radiosurgery program was expanded to include patients with endocrine and metabolic disorders of the pituitary gland, i.e., acromegaly, Cushing's disease, Nelson's syndrome, prolactinsecreting adenomas and chromophobe adenomas [8,11,13,14,15,16].…”
Section: Introductionmentioning
confidence: 99%
“…In 1958, the charged-particle radiosurgery program was expanded to include patients with endocrine and metabolic disorders of the pituitary gland, i.e., acromegaly, Cushing's disease, Nelson's syndrome, prolactinsecreting adenomas and chromophobe adenomas [8,11,13,14,15,16]. ·In the 441 patients with hormone-secreting tumors, the therapeutic goal has been to destroy or inhibit the growth of the pituitary tumor and control hormonal hypersecretion, while preserving a functional rim of tissue with normal hormone-secreting capacity, and minimizing neurologic injury [11,13,15]; an additional 34 patients with nonsecreting chromophobe adenomas were treated to alleviate sequelae of an expanding mass lesion (Table 1).…”
Section: Introductionmentioning
confidence: 99%
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“…The radiosurgical treatment of AVMs is based on the delivery of a uniform radiation dose to the arterial com~onent of the lesion while attempting to spare the venous stru.ctures, damage to which could compromise normal tissue [3,4,8,9].…”
mentioning
confidence: 99%