We present a comparative study of the charmed baryon−nucleon interaction based on different theoretical approaches. For this purpose, we make use of i) a constituent quark model tuned in the light-flavor baryon−baryon interaction and the hadron spectra, ii) existing results in the literature based both on hadronic and quark-level descriptions, iii) (2+1)-flavor lattice QCD results of the HAL QCD Collaboration at unphysical pion masses and their effective field theory extrapolation to the physical pion mass. There is a general qualitative agreement among the different available approaches to the charmed baryon−nucleon interaction. Different from hadronic models based on one-boson exchange potentials, quark−model based results point to soft interactions without twobody bound states. They also support a negligible channel coupling, due either to tensor forces or to transitions between different physical channels, Λ c N − Σ c N . Short-range gluon and quarkexchange dynamics generate a slightly larger repulsion in the 1 S 0 than in the 3 S 1 Λ c N partial wave.A similar asymmetry between the attraction in the two S waves of the Λ c N interaction also appears in hadronic approaches. A comparative detailed study of Pauli suppressed partial waves, as the 1 S 0 (I = 1/2) and 3 S 1 (I = 3/2) Σ c N channels, would help to disentangle the short-range dynamics of two-baryon systems containing heavy flavors. The possible existence of charmed hypernuclei is discussed. * Electronic address: humberto@esfm.ipn.mx † Electronic address: valcarce@usal.es ‡ Electronic address: carames@usal.es