Cheilitis glandularis: An unusual histopathologic presentation

Cheilitis glandularis: A clinicopathological study in 22 patients

“…The condition is considered rare; there are few published case series, 3 and most reports refer to single cases. [4][5][6][7][8] The clinical picture of CG consists of variable degrees of macrocheilia accompanied by the presence of red, dilated ostia of minor salivary glands on the vermilion area (this last finding is usually absent in the normal lip). A thick, mucoid material can be obtained from these ostia by manual expression.…”

Cystadenoma: a rare tumor originated in minor salivary gland

“…In 2003, a case of this lesion was described, what was initially diagnosed as papillary cystadenoma since an incisional biopsy showed a lesion of papillary arrangement that exhibited marked oncocytic ductal hyperplasia and squamous metaplasia (20) . However, the clinical aspect in that case strongly contributed to the diagnosis of the initial phase of cheilitis glandularis since the lesion clinically manifested as multiple nodules in the lower lip, as reported for a simple subtype.…”

“…These histopathological patterns agree with those defined for cystadenoma (1,5,7,15,22) , and the lesion was therefore diagnosed as cystadenoma. However, in view of the complexity and histomorphological diversity of salivary gland tumors, the differential diagnosis of cystadenoma should include intraductal papilloma (19) , cystadenocarcinoma (6) , lowgrade mucoepidermoid carcinoma (17) , Warthin tumor (1) and cheilitis glandularis (20) , which are discussed below.…”

Solar cheilosis: An ominous precursor

“…31,32 Cheilitis glandularis is an inflammatory disorder of the lower lip salivary glands that typically occurs in older men. 33,34 Patients with cheilitis glandularis often complain of pain while eating or upon palpation. 35 Angular cheilitis, also known as angular stomatitis, is occasionally associated with conditions such as oral candidiasis and chronic use of dentures, as well as systemic disorders, such as pernicious anemia, and HIV infection.…”