Chemical Composition and Biological Activity of the Leaf Essential Oil of Zanthoxylum Oxyphyllum

Borah, R. C.; Saikia, Kalpita; Talukdar, AK; Kalita, M. C.

doi:10.1055/s-0032-1307608

Cited by 6 publications

(1 citation statement)

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“…Plant extracts and isolated compounds are considered to be a potential alternative approach against various stages and species of mosquitoes due to their excellent properties like environment safety nature. Besides, the bioactive ingredients of the plants can also act as ovicidal, repellent, oviposition, deterrence, reduction of recundity and fertility, larvicidal and also insect grown regulator 2 . One of the available methods used for the control of mosquitoes is by using chemical insecticides.…”

Section: Introductionmentioning

confidence: 99%

Larvicidal Carbazole Alkaloids from Murraya koenigii Against Dengue Fever Mosquito Aedes aegypti Linnaeus

Sukari¹,

Noor²,

Bakar³

et al. 2013

Asian J. Chem.

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Phytochemical studies on different parts of Murraya koenigii (L.) have resulted in the isolation of six carbazole alkaloids which have been identified as mahanimbine (1), girinimbine (2), murrayacine (3), murrayanine (4), murrayafoline-A (5) and 3-methylcarbazole (6) together with β-sitosterol. The structures of these compounds were established using spectroscopic techniques. The crude extracts and chemical constituents obtained from the isolation work were tested on its larvicidal activity against dengue fever mosquito, Aedes aegypti. Hexane extract from stem bark, roots and leaves of Murraya koenigii showed strong activity against Aedes aegypti followed by chloroform extract of the roots and leaves. Methanol extract of the leaves also showed strong activity while methanol extract of the roots showed moderate activity. Besides, chloroform and methanol extracts from stem bark showed strong activity. Similarly, pure compounds isolated from the plant, mahanimbine (1), girinimbine (2), murrayacine (3), murrayanine (4) and murrayafoline A (5) exhibited strong activity against Aedes aegypti with LC50 values of less than 3 µg/mL.

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Section: Introductionmentioning

confidence: 99%