Chemical composition and in vitro antibacterial activities of traditional medicinal plant: Olea sp

Khayat, Suzan; Al-Zahrani, Salha H.; Basudan, Nour; Alzahrani, Nourah Hassan; Subahi, Jawaher A.

doi:10.4066/biomedicalresearch.29-17-3106

Cited by 4 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Phytochemical screening of Olea sp. demonstrated a high concentration of tannins as well as flavonoids, steroids, terpenoids, and coumarins (Khayat et al, 2018).…”

Section: Groups Of Antimicrobial Secondary Metabolitesmentioning

confidence: 99%

Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants

2019

View full text Add to dashboard Cite

Antibiotic-resistant microorganisms have been an ever-growing concern over the past years. This has led researchers to direct their attention onto plants to be able to discover new possible antimicrobial compounds. The Middle East encompasses a wide spectrum of plant diversity with over 20,000 different species in habitats ranging from deserts to snow-capped mountains. Several plant secondary metabolites and their derivatives have been identified as possible antimicrobial agents. Among the secondary metabolites studied, alkaloids and polyphenols have shown strong antimicrobial activity. Polyphenols are one of the most numerous and diverse group of secondary metabolites; their antioxidant properties provide the basis for antimicrobial effects. Alkaloids provided the underlying structure for the development of several antibiotics with a diverse range of action. The ability of some plant secondary metabolites to act as resistance-modifying agents is a promising field in mitigating the spread of bacterial resistance.

show abstract

“…Phytochemical screening of Olea sp. demonstrated a high concentration of tannins as well as flavonoids, steroids, terpenoids, and coumarins (Khayat et al, 2018).…”

Section: Groups Of Antimicrobial Secondary Metabolitesmentioning

confidence: 99%

Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants

2019

View full text Add to dashboard Cite

show abstract

“…and S. aureus, ethanolic extract demonstrated the higher antibacterial and phytochemical screening of Olea sp. showed high concentration of tannins as well as flavonoids, steroids, terpenoids, and coumarins [62]. Zingiber officinale and Curcuma longa were extracted by methanol and water and experimented for their antibacterial activity against: S. aureus, S. pyogenes, P. aeruginosa and E. coli, Aqueous and methanolic extracts of Curcuma longa illustrated higher antibacterial activity than both extracts of Z. officinale depending on the diameters of inhibition zones, tannins is presence in the extracts of the two plants according to phytochemical screening [63].…”

Section: Tanninsmentioning

confidence: 99%

Survey of Antagonistic Action and the Mechanism of these Actions that Terpens, Phenols and their Derivatives Possess Against Different Pathogenic Agents

Najem¹

2021

ANJS

View full text Add to dashboard Cite

Folk medicine or herbal treatment has been used for centuries by different ancient civilizations against various ailment agents, herbal medicine has been dragged attention by researchers in different medical branches focusing on therapeutically characteristic features of each plant against different pathogenic agents responsible for most devastating and terrifying diseases, in addition to thorough investigation for the phytochemical compounds in each plant responsible for its potent against pathogens. Thus, this study highlights on two major groups of secondary metabolic compounds: terpens, phenols and their derivatives as antimicrobial agents against different bacterial and fungal strains especially drug resistant bacteria which responsible for the infectivity of treatments of most infectious diseases. Furthermore, mechanisms of actions of these secondary metabolites are reviewed as the causative factors responsible for the antimicrobial activity of plants and the promising results which have been achieved in multiply these activities by making combination between these natural products and chemical drugs.

show abstract

Efficacy of Acacia nilotica aqueous extract in treating biofilm-forming and multidrug resistant uropathogens isolated from patients with UTI syndrome

Elamary

Albarakaty

Salem

2020

Sci Rep

View full text Add to dashboard Cite

Escherichia coli is the dominant bacterial cause of UTI among the uropathogens in both developed and developing countries. This study is to investigate the effect of Acacia nilotica aqueous extract on the survival and biofilm of isolated pathogens to reduce UTIs diseases. A total of 170 urine samples were collected from Luxor general hospital and private medical analysis laboratories in Luxor providence, Egypt. Samples were screened for the incidence of uropathogens by biochemical tests, antibiotics susceptibility, detection of virulence, and antibiotic-resistant genes by multiplex PCR, biofilm formation, and time-killing assay. Escherichia coli is by far the most prevalent causative agent with the percentage of 73.7% followed by Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeuroginosa, and Acinetobacter baumanii. Isolates were multidrug-resistant containing blaTEM, blaSHV, blaCTX, qnrs, and aac(3)-Ia resistant genes. All isolates were sensitive to 15–16.7 mg ml−1 of Acacia nilotica aqueous extract. Time killing assay confirmed the bactericidal effect of the extract over time (20–24 h). A high percentage of 3-Cyclohexane-1-Carboxaldehyde, 2,6,6-trimethyl (23.5%); á-Selinene (15.12%); Oleic Acid (14.52%); Globulol (11.35%) were detected among 19 bioactive phytochemical compounds in the aqueous extract of A. nilotica over the GC-mass spectra analysis. The plant extract reduced significantly the biofilm activity of E. coli, K. pneumoniae, P. mirabilis, and P. aeuroginosa by 62.6, 59. 03, 48.9 and 39.2%, respectively. The challenge to improve the production of A. nilotica phytochemicals is considered a very low price for the return.

show abstract

Chemical composition and in vitro antibacterial activities of traditional medicinal plant: Olea sp

Abstract: The aim of this work is to study the phytochemical and antibacterial screening of Olea sp. leaves

Cited by 4 publications

References 14 publications

Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants

Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants

Survey of Antagonistic Action and the Mechanism of these Actions that Terpens, Phenols and their Derivatives Possess Against Different Pathogenic Agents

Efficacy of Acacia nilotica aqueous extract in treating biofilm-forming and multidrug resistant uropathogens isolated from patients with UTI syndrome

Contact Info

Product

Resources

About