CHEMICAL COMPOSITION, ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF &lt;i&gt;EUCALYPTUS CHAPMANIANA&lt;/i&gt; GROWN IN IRAQ

Sulaiman, Ghassan M.; Marzoog, Thorria R.; Mohammed, Wasnaa Hatif; Bagnati, Renzo

doi:10.3844/ajabssp.2014.78.88

Cited by 5 publications

(3 citation statements)

References 45 publications

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“…Essential oil has been cultivated for medicinal oil production in many parts of the world. Numbers of reports are available all around the world which shows the antibacterial [8][9][10][11] and antioxidant of Eucalyptus Leaves [12][13][14][15][16] . Eucalyptus essential oil is extracted from Eucalyptus globulus of the Myrtaceae family and is also known as Tasmanian blue gum or blue gum.…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study of the Chemical Composition of the Essential oil from Eucalyptus globulus Growing in Dehradun (india) and Around the World

Joshi¹,

Sharma²,

Bachheti³

et al. 2016

Orient. J. Chem

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Due to increasing use of natural products, essential oil are also in great demand in various field such as pharmaceutical, cosmetic and food industries. The aim of this study is to determine the chemical composition of essential oil of Eucalyptus globulus grown in Dehradun, India. A total of twenty seven compounds were identified from the essential oil, by Gas chromatography mass spectroscopy representing 100 % of the total oil. The dominant compounds being Eucalyptol (1,8-cineole) 54.79 %, â-pinene 18.54 % á-pinene 11.46 %, â-eudesmol 4.68%, á-phellandrene 2.06% Para cymene 1.60% and Gamma-eudesmol 1.20%. Comparison of the literature on essential oil from Eucalyptus globulus around the world (seven countries) suggested eight compounds that were uniquely present only in Dehradun essential oil sample. Thus, the present study suggested that Eucalyptus globulus growing in Dehradun contains several volatile compounds that are not reported in other Eucalyptus globulus essential oil around the world.

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Section: Introductionmentioning

confidence: 99%

A Comparative Study of the Chemical Composition of the Essential oil from Eucalyptus globulus Growing in Dehradun (india) and Around the World

Joshi¹,

Sharma²,

Bachheti³

et al. 2016

Orient. J. Chem

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“…Treatments of leukemia are mainly with chemotherapy, medical radiation therapy, hormone treatments and bone marrow transplantation [7]. Despite tremendous progress in cancer therapy research, there are long-term side effects of chemotherapy and other treatments in leukemia [8,9,10]. Medicinal plants with the ancient history of human use have been considered one of the important and reliable sources to discover promising therapeutic agents in disease conditions, including cancer chemo-preventive drugs [11].…”

Section: Introductionmentioning

confidence: 99%

Ethno Botanical Survey, Anti-leukemia and Anticlastogenic Potential of Medicinal Plants used for Treatment of Leukemia in Oyo State Nigeria

Adetutu

Owoade

Alabi

et al. 2020

JOCAMR

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Ethnopharmacological Relevance: Leukemia, a cancer of the blood and bone marrow is responsible for about 222.000 deaths annually. The side effects of chemotherapy in leukemia treatment have necessitated the search for natural products especially medicinal plants as alternative therapy. Aim: This study surveyed common plants used for treating leukemia in Oyo state, Nigeria and assessed the anti-leukemic and anti-clastogenic activities of fractions of Nymphaea lotus. Methods: Semi-structured questionnaire (1000) was used to collect the ethnobotanical data among the traditional healers. Leukemia was induced in albino mice with 400 mg/kg body weight of benzene intraperitoneally. Aqueous extracts (120mg/kg/bw), fractions and 5-florouracil (25mg) was administered to mice of different groups. The anti-leukemic, anti-clastogenic, antioxidant, hepatoprotective activities and hematological parameters were determined. N. lotus was subjected to gas-chromatography mass spectroscopy analysis. Results: The ethnobotanical survey recorded 89 plant species with their local names and parts used in the traditional therapeutic preparations. Seven plants (Pistiastratiotes (2.5%), Nymphaea lotus (1.4%), Piper guineense (1.7%), Securinega virosa (2.5%), Calotropis procera (3.4%), Morinda lucida (2.5%) and Xylopia aethiopica (4.5%) with the highest frequency of citation were selected for anti-leukemic and anti-clastogenic screening. The aqueous extract of N. lotus and M. lucida displayed anti-leukemic potential. M. lucida and X. aethiopica improved the hematological parameters. Ethyl acetate fraction of N. lotus significantly (p<0.05) reduced the number of micronucleated polychromatic erythrocyte in the bone marrow and showed anti-leukemic activity. Fractions of N. lotus restored the hematological parameters and exhibited significant (p<0.05) antioxidant activity. Histological observation revealed improvement in the liver general cyto-architecture of mice treated with ethyl acetate and butanol fractions of N. lotus. Some known compounds were identified in ethyl acetate fraction of N. lotus. Conclusion: Most of the species tested had some anti-leukemic effect in mice, which to some extent supports their traditional inclusion in herbal preparations for treatment of leukemia. The study also identified potential anti-leukemic compounds in N. lotus extract. The study also identified potential anti-leukemic compounds in N. lotus extract.

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“…The EGEO is widely used for aromatherapy in Europe and Africa (Sulaiman et al, 2014). EGEO has been positioned under Generally Regarded as Safe (GRAS) class by Food and Drug Administration of USA and classified as non-toxic.…”

Section: Introductionmentioning

confidence: 99%

LIQUID AND VAPOUR PHASE ANTIBACTERIAL ACTIVITY OF <i>EUCALYPTUS GLOBULUS</i> ESSENTIAL OIL = SUSCEPTIBILITY OF SELECTED RESPIRATORY TRACT PATHOGENS

Nadjib¹,

Amine²,

Kameli³

et al. 2014

American Journal of Infectious Diseases

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Essential Oils (EO) produced by medicinal plants have been traditionally used for respiratory tract infections and are used nowadays as ethical medicines for colds. Although several studies of Eucalyptus Globulus Labill. Essential Oil (EGEO) have been reported, there are no reports describing vapour activity of EGEO against bacterial respiratory tract pathogens. The aim of this study was to test the efficacy of the Algerian EGEO against some respiratory tract pathogens by disc diffusion and vapour diffusion methods at different concentrations. Chemical composition of the EGEO was analysed by Gas Chromatography-Mass Spectrometry. Fresh leaves of E. globulus on steam distillation yielded 0.96% (v/w) of essential oil whereas the analysis resulted in the identification of a total of 11 constituents, 1.8 cineole (85.8%), α-pinene (7.2%) and β-myrcene (1.5%) being the main components. By disc diffusion method, EGEO showed potent antimicrobial activity against Gram-positive more than Gram-negative bacteria. The Diameter of Inhibition Zone (DIZ) varied from 69 mm to 75 mm for Staphylococcus aureus and Bacillus subtilis (Gram +) and from 13 to 42 mm for Enterobacter sp and Escherichia coli (Gram-), respectively. However, the results obtained by both agar diffusion and vapour diffusion methods were different. Significantly higher antibacterial activity was observed in the vapour phase at lower concentrations. A. baumanii and Klebsiella pneumoniae were the most susceptible strains to the oil vapour with DIZ varied from 38 to 42 mm. Therefore, smaller doses of EO in the vapour phase can be inhibitory to pathogenic bacteria. Else, the DIZ increased with increase in concentration of the oil. There is growing evidence that EGEO in vapour phase are effective antibacterial systems and appears worthy to be considered for practical uses in the treatment or prevention of patients with respiratory tract infections or as air decontaminants in hospital. The present study indicates that EGEO has considerable antimicrobial activity, deserving further investigation for clinical applications.

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CHEMICAL COMPOSITION, ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF <i>EUCALYPTUS CHAPMANIANA</i> GROWN IN IRAQ

Cited by 5 publications

References 45 publications

A Comparative Study of the Chemical Composition of the Essential oil from Eucalyptus globulus Growing in Dehradun (india) and Around the World

A Comparative Study of the Chemical Composition of the Essential oil from Eucalyptus globulus Growing in Dehradun (india) and Around the World

Ethno Botanical Survey, Anti-leukemia and Anticlastogenic Potential of Medicinal Plants used for Treatment of Leukemia in Oyo State Nigeria

LIQUID AND VAPOUR PHASE ANTIBACTERIAL ACTIVITY OF <i>EUCALYPTUS GLOBULUS</i> ESSENTIAL OIL = SUSCEPTIBILITY OF SELECTED RESPIRATORY TRACT PATHOGENS

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