Chemical composition of essential oil of Jatropha curcas L. leaves and its antioxidant and antimicrobial activities

Babahmad, Rachid Ait; Aghraz, Abdellah; Boutafda, Aziz; Papazoglou, Eleni G.; Tarantilis, Petros Α.; Kanakis, Charalabos D.; Hafidi, Mohamed; Ouhdouch, Yedir; Outzourhit, A.; Ouhammou, Ahmed

doi:10.1016/j.indcrop.2018.05.030

Cited by 44 publications

(16 citation statements)

References 37 publications

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“…Interest in this species has been increasing, due to J. curcas rapid growth and easy propagation, contributing to its use as an alternative energy source, and the identification of several secondary metabolites in this plant with medicinal importance [1,2]. Crude extracts, essential oils and isolated compounds from J. curcas are used in a wide range of pharmacological activities, such as antiinflammatory, antioxidant, antimicrobial, antiviral, molluscicide, larvicidal, anticancer, antidiabetic, procoagulant, anticoagulant, hepatoprotective, analgesic, healing and abortifacient [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

The Mitigating Effect of Jatropha curcas L. Latex against Genotoxicity Induced by Doxorubicin

Bailão

Pereira

Silva

et al. 2019

EJMP

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Jatropha curcas (Euphorbiaceae) is a multiple purpose lacticiferous plant with potential for biodiesel production and medicinal uses. There is in the literature different analyses about the toxic and cytogenotoxic effects of J. curcas extracts, but few information about latex toxicity. In addition, few models were employed to evaluate the toxicity response to J. curcas latex, and the toxicity in in vivo mammal’s model has not been tested yet. The cytotoxic, mutagenic and antimutagenic potential of J. curcas latex were investigated using mouse bone marrow erythrocytes. The results indicated a cytotoxic and mutagenic potential of this latex to mammalian cells. But, when J. curcas latex was co-administrated with doxorubicin (DXR – chemotherapy medication), a reduction in the number of micronuclei was observed, indicating an interaction between J. curcas latex and DXR. The interaction of latex with DXR can cause a reduction in the activity of this drug and impair the treatment of its users. Moreover, there is a lack of data on herb–drug interactions, what should be more investigated to safeguard the wellbeing of patients.

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Section: Introductionmentioning

confidence: 99%

The Mitigating Effect of Jatropha curcas L. Latex against Genotoxicity Induced by Doxorubicin

Bailão

Pereira

Silva

et al. 2019

EJMP

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“…Then the soaked discs were placed in a microbial strain plate. The inhibition diameter was measured with a vernier caliper and the MIN and MAX effects were tested 27 .…”

Section: Methodsmentioning

confidence: 99%

Antioxidant and antibacterial insights into the leaves, leaf tea and medicinal roots from Astragalus membranaceus (Fisch.) Bge.

Samuel

Huang

Chen

et al. 2021

Sci Rep

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Used as traditional Chinese medicine, Astragalus membranaceus (Fisch.) Bge. (A. membranaceus) roots are also used as tonic food material in a wide range of applications, while the leaves are left in the field, unused. Therefore, comprehensively exploring and utilizing the leaves will inevitably reduce the associated resource waste and environment pollution. In this study, the plant leaves were processed into tea using green tea processing technology. Bioactive components, antioxidant and antibacterial activities of the Leaf Tea (LT) and Dry Leaves (DL) were studied, and compared to that of the Dry Roots (DR). The results showed that the polysaccharides content (POL) in the DR (20.44%) was twice as high as the DL (10.18%) and LT (8.68%). However, the DL contained 36.85% more water-soluble extracts (WSE), 35.09% more ethanol-soluble extracts (ESE), 409.63% more total flavonoid content (TFC), 221.01% more total phenolic content (TPC) and 94.34% more proteins, and the LT contained 26.21% more WSE, 40.64% more ESE, 326.93% more TFC, 191.90% more TPC and 37.71% more proteins. The total amino acid (AA) content in the DR was 8.89%, while in that of the DL and LT were 24.18% and 28.96% respectively, nearly 3-times higher than that of the DR. The antioxidant activity of DR was much lower than those of DL and LT, both of which had antioxidant activity closer to that of Vitamin C (VC) and the antioxidant activities were even stronger when the optimal concentration was reached. Except for Aspergillus niger and Staphylococcus aureus, the DL and DR exhibited inhibition activities to Salmonella, Bacillus subtilis, Escherichia coli and yeast, while the LT had antimicrobial activities against all the strains except for A. niger. In summary, compared with the most commonly used DR, the DL and LT from A. membranaceus contained higher bioactive components, and stronger antioxidant and antimicrobial activities. Producing leaf tea may be an appropriate way to economically and reasonably utilize the plant leaves which are by-products.

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“…The DPPH radical scavenging activity was measured based on the method described previously [24] with some modifications. In brief, 50 µL of EOs at different concentrations were mixed with 2 mL of DPPH (60 µM) methanol solution.…”

Section: Methodsmentioning

confidence: 99%

Variation in Chemical Composition and Biological Activities of Flos Chrysanthemi indici Essential Oil under Different Extraction Methods

et al. 2019

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Flos Chrysanthemi indici, an important medicinal and aromatic plant in China, is considered to have many different preservative and pharmacological properties. Considering the capability of essential oils (EOs), the present study is conducted to compare different extraction methods in order to improve yield and biological activities. Hydro-distillation (HD), steam-distillation (SD), solvent-free microwave extraction (SFME), and supercritical fluid extraction (SFE) are employed to prepare EOs from Flos Chrysanthemi indici. A total of 71 compounds are assigned by gas chromatography/mass spectrometry (GC–MS) in comparison with retention indices. These include 32 (HD), 16 (SD), 31 (SFME) and 38 (SFE) compounds. Major constituents of EOs differ according to the extraction methods were heptenol, tricosane, camphor, borneol, and eucalyptol. EOs extracted by SFME exhibit higher antioxidant activity. All EOs show varying degrees of antimicrobial activity, with minimum inhibitory concentration (MIC) ranging from 0.0625 to 0.125 mg/mL and SFME and SFE prove to be efficient extraction methods. EOs alter the hyphal morphology of Alternaria alternata, with visible bumps forming on the mycelium. Overall, these results indicate that the extraction method can significantly influence the composition and biological activity of EOs and SFME and SFE are outstanding methods to extract EOs with high yield and antimicrobial activity.

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Chemical composition of essential oil of Jatropha curcas L. leaves and its antioxidant and antimicrobial activities

Cited by 44 publications

References 37 publications

The Mitigating Effect of Jatropha curcas L. Latex against Genotoxicity Induced by Doxorubicin

The Mitigating Effect of Jatropha curcas L. Latex against Genotoxicity Induced by Doxorubicin

Antioxidant and antibacterial insights into the leaves, leaf tea and medicinal roots from Astragalus membranaceus (Fisch.) Bge.

Variation in Chemical Composition and Biological Activities of Flos Chrysanthemi indici Essential Oil under Different Extraction Methods

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