Chemical peels for the management of melasma and hyperpigmentation

Abstract

Melasma is often a difficult disease to treat, and can be psychologically distressing to patients. Currently, the gold standard for the treatment of melasma is hydroquinone. While this treatment has been used for many years, it does not come without risks with overuse. Chemical peels have also become an option for the treatment of melasma, but their efficacy and safety in comparison to hydroquinone has not yet been established. This review aims to investigate the various types, efficacy, and safety of chemical peels used to treat melasma.

Topical AHA in Dermatology: Formulations, Mechanisms of Action, Efficacy, and Future Perspectives

“…The exploration of novel AHAs has further expanded the range of treatment options for various skin conditions. Mandelic acid, a naturally derived AHA, has been used in the treatment of hyperpigmentation and melasma due to its anti-inflammatory properties, which make it less irritating than other peels and thus safer for sensitive skin [20]. These findings underscore the potential of novel AHAs in dermatology.…”