This is a review of a patient encounter that underscores the common trend of insufficient inclusivity and lack of diversity regarding skin of color representation in teaching materials including textbooks in the medical education setup. A Black woman who was treated with carbamazepine for trigeminal neuralgia after a dental procedure presented with upper airway breathing difficulties and facial pain and swelling. After doubling her dose of carbamazepine as advised by her primary care physician, her symptoms continued to worsen, and she was treated in the emergency department for a presumed allergic reaction of unknown etiology. Two days later, her symptoms progressively worsened. She self-admitted to the emergency department, where she required cardiopulmonary resuscitation. Eventually, the formal diagnosis of carbamazepine-induced Stevens-Johnson syndrome (SJS) was made based on history, clinical presentation, and skin biopsy.The nature of the disease progression in this case prompted our investigation into the lack of representation of skin of color in current medical training resources regarding SJS. Our assessment demonstrates that there is a significant underrepresentation of SJS in skin of color in medical educational resources. Increased inclusivity of skin disorders in patients of color is crucial in training healthcare professionals to recognize life-threatening cutaneous disorders quickly and accurately in such patients.

Tinea is a superficial fungal infection of the skin. Gyrate erythemas are reactive conditions that present as annular red lesions. A 61-year-old woman was diagnosed with tinea corporis whose skin lesions morphologically mimicked a gyrate erythema. She presented with diffuse annular plaques affecting the left side of her chest and abdomen that did not respond to a combination antifungal-corticosteroid cream for six-month duration. The appearance and clinical differential diagnosis included a gyrate erythema. Initial evaluation of the skin biopsy from the lesion's edge demonstrated a spongiotic dermatitis, and staining for fungal organisms was negative. However, deeper sections and a different fungal stain revealed hyphae in the stratum corneum and established a diagnosis of tinea corporis. The PubMed database was used to review the following terms: tinea corporis, gyrate erythema, and tinea incognito. Relevant papers and references cited in those papers that were generated by the search were used. Tinea corporis, especially if previously treated with topical corticosteroids, can masquerade as other dermatoses including a gyrate erythema. Correlation of clinical presentation and pathology findings is essential, especially if the biopsy results do not confirm the suspected clinical diagnosis. Consideration to perform deeper sections or additional special stains or both should also be entertained when the initial pathology observations do not support the presumptive diagnosis based on clinical morphology and history.

Seborrheic keratosis is an epithelial-derived benign neoplasm, which presents as a solitary tumor or multiple lesions. It is an acquired skin tumor that is frequently observed in older individuals. Benign neoplasms, as well as premalignant or malignant tumors, can mimic the clinical appearance of a seborrheic keratosis. A man presented with a chronic lesion on his abdomen that had changed in the color and size. The suspected diagnosis was a seborrheic keratosis. However, the microscopic evaluation of a biopsy tissue specimen established a diagnosis of a pigmented squamous cell carcinoma in situ. In addition to squamous cell carcinoma in situ and squamous cell carcinoma, other malignant tumors, premalignant lesions, and benign lesions can mimic a seborrheic keratosis. If a patient presents with a presumptive seborrheic keratosis that has changed in appearance and for which malignancy is also suspected, a biopsy may be helpful for diagnostic clarification to either confirm that the lesion is indeed a seborrheic keratosis or to establish the diagnosis of the lesion that mimics a seborrheic keratosis.

Melasma is often a difficult disease to treat, and can be psychologically distressing to patients. Currently, the gold standard for the treatment of melasma is hydroquinone. While this treatment has been used for many years, it does not come without risks with overuse. Chemical peels have also become an option for the treatment of melasma, but their efficacy and safety in comparison to hydroquinone has not yet been established. This review aims to investigate the various types, efficacy, and safety of chemical peels used to treat melasma.

Postinfantile giant cell hepatitis (PIGCH), also known as syncytial giant cell hepatitis, continues to be a poorly defined and rare disease presentation in the adult population. Although a common finding in neonates, there is limited literature on the disease process, causes, and treatment success of PIGCH in adults. A strong association between autoimmune disorders and PIGCH, considerably so in the case of autoimmune hepatitis, has been established. However, there have been limited to no reports of PIGCH secondary to rheumatoid arthritis. Our clinical case aims to bring forth a vignette of PIGCH to spotlight this ill-defined disease in the adult population and highlight some of the proposed causes, treatments, and laboratory markers.