Chemical profile and in-vitro pharmacological activities of yellow pigment extracted from Arthrobacter gandavensis

Numan, Muhammad; Bashir, Samina; Mumtaz, Roqayya; Tayyab, Sibgha; Ullah, Ikram; Khan, Abdul Latif; Al‐Harrasi, Ahmed

doi:10.1016/j.procbio.2018.08.033

Cited by 7 publications

(6 citation statements)

References 38 publications

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“…In Figure 3 A the highest and lowest DPPH scavenging activities were 70.0 at 0.4 µM and 41.65% at 0.005 µM, respectively. Similar results of DPPH-free radical scavenging potential were obtained from yellow pigment extracted from the bacteria Arthrobacter gandavensis [ 4 ]. In Figure 3 B the highest and lowest scavenging activities were 97.0 at 0.4 µM and 68.0% at 0.005 µM, respectively.…”

Section: Resultssupporting

confidence: 75%

“…It has been reported that greater than 75% of the treatments used for infective illness are obtained from natural sources [ 3 ]. Among many benefits of microbes, the production of natural pigments has been acquiring popularity due to their commercial and medicinal values [ 4 ]. Microorganisms-derived pigments have been pointed up in diverse applications, such as food, cosmetics, textile and pharmaceutical industries [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant Activity Evaluation of FlexirubinType Pigment from Chryseobacterium artocarpi CECT 8497 and Related Docking Study

et al. 2021

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The current research is focused on studying the biological efficacy of flexirubin, a pigment extracted from Chryseobacterium artocarpi CECT 8497.Different methods such as DPPH, H2O2, NO•, O2•-, •OH, lipid peroxidation inhibition by FTC and TBA, ferric reducing and ferrous chelating activity were carried out to evaluate the antioxidant activity of flexirubin. Molecular docking was also carried out, seeking the molecular interactions of flexirubin and a standard antioxidant compound with SOD enzyme to figure out the possible flexirubin activity mechanism. The new findings revealed that the highest level of flexirubin exhibited similar antioxidant activity as that of the standard compound according to the H2O2, •OH, O2•-, FTC and TBA methods. On the other hand, flexirubin at the highest level has shown lower antioxidant activity than the positive control according to the DPPH and NO. and even much lower when measured by the FRAP method. Molecular docking showed that the interaction of flexirubin was in the binding cavity of the SOD enzyme and did not affect its metal-binding site. These results revealed that flexirubin has antioxidant properties and can be a useful therapeutic compound in preventing or treating free radical-related diseases.

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Section: Resultssupporting

confidence: 75%

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity Evaluation of FlexirubinType Pigment from Chryseobacterium artocarpi CECT 8497 and Related Docking Study

et al. 2021

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“…The temperature was increased again at a rate of 20 °C/min up to 280 °C and held for 3 min. A split ratio of 1:50 was maintained with Helium being used as inert carrier gas at a flow rate of 1 mL/min [ 56 , 62 , 63 ].…”

Section: Methodsmentioning

confidence: 99%

Production, purification, and process optimization of intracellular pigment from novel psychrotolerant Paenibacillus sp. BPW19

Padhan

Poddar

Sarkar

et al. 2021

Biotechnology Reports

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“…Based on GCMS, the bacterial pigment contained six compounds: -thujene, phosphorous acid, glycerol, 2-butene-1-ol-3-methylacetate, camphor, and terpinene-4-ol. On the contrary, based on high-performance liquid chromatography analysis, the bacterial pigment contained 14 different compounds: gallic acid derivative, neoxanthin, capsorubin, carotenoid P468, violaxanthin, gallic acid derivative, monogalloylhexoside, ellagitannin, alltransviolaxanthin, -carotene, caffeic acid derivative, quercetin-3-O-rutinoside 7-O-glucoside, bis-HHDPglucose, and -carotene (Numan et al, 2018). Moreover, V. owensii TNKJ.CR.24-7 isolated from coral samples produced -carotene, which inhibited ESBL E. coli, K. pneumoniae, and methicillin-resistant S. aureus strain (Sibero et al, 2019).…”

Section: Antibacterial Activity Of Carotenoid Extracts From Heterotro...mentioning

confidence: 99%

Antibacterial Activity of Carotenoid Pigments Produced by Heterotrophic Bacteria from Seawater in Krakal Coastal Area, Yogyakarta, Indonesia

Sidin

Retnaningrum

2022

Squalen Bull. Marine Fisheries Postharvest Biotech.

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Investigating natural pigments resulting from marine bacterial secondary metabolites is important because of their broad benefits in the food, pharmaceutical, cosmetic, and textile industries. In this study, 52 isolates of pigmented bacteria were isolated from seawater in the Krakal coastal area, Yogyakarta, Indonesia. Seven bacterial isolates showed high pigment stability. Profiling of pigment extracts using a mixture of acetone and methanol with UV–Vis spectrophotometric reading showed that the compounds produced were carotenoids. The highest total carotenoid content with UV–Vis spectrophotometric reading at 480 nm was produced by the Kral-3 isolate (1800 mg/g), followed by Kral-15 (1698.9 mg/g) and Kral-25 (797.2 mg/g) isolates. Analysis of the antibacterial activity of the carotenoid extracts of Kral-3, Kral-15, and Kral-25 isolates using the agar well diffusion method revealed a very strong inhibition score against Escherichia coli. In addition, the carotenoid extract of the Kral-3 isolate showed a strong inhibition score against Staphylococcus aureus, whereas the Kral-15 and Kral-25 isolates showed moderate inhibition scores. Based on the 16S rRNA gene analysis, the Kral-3, Kral-15, and Kral-25 isolates were identified as Kocuria rhizophilla, Calidifontibacter sp., and Rhodococcus ruber, respectively. Based on the findings, the novel bacterial strains are a potential bioresource for the commercial production of natural carotenoids.

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Chemical profile and in-vitro pharmacological activities of yellow pigment extracted from Arthrobacter gandavensis

Cited by 7 publications

References 38 publications

Antioxidant Activity Evaluation of FlexirubinType Pigment from Chryseobacterium artocarpi CECT 8497 and Related Docking Study

Antioxidant Activity Evaluation of FlexirubinType Pigment from Chryseobacterium artocarpi CECT 8497 and Related Docking Study

Production, purification, and process optimization of intracellular pigment from novel psychrotolerant Paenibacillus sp. BPW19

Antibacterial Activity of Carotenoid Pigments Produced by Heterotrophic Bacteria from Seawater in Krakal Coastal Area, Yogyakarta, Indonesia

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