Chemical structure of a novel heteroglycan polysaccharide isolated from the biomass of Ophiocordyceps Sobolifera

Tran, Thi Van Thi; Tran, Van Khoa; Ho, Xuan Anh Vu; Sơn, Lê Lâm; Le, Trung Hieu; Nguyen, Thi Hong Chuong; Nguyen, Chinh Chien; Kim, Soo Young; Le, Quyet Van

doi:10.1016/j.molstruc.2021.129986

Cited by 9 publications

(4 citation statements)

References 66 publications

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“…The water-soluble polysaccharides were collected through a two-step extraction, as shown in Scheme . Briefly, the defatted M.…”

Section: Methodsmentioning

confidence: 99%

“…The water-soluble polysaccharides were collected through a two-step extraction, as shown in Scheme 2 . 27 Briefly, the defatted M. smilacifolium root powder (50 g) was dried and subjected to ethanol 96% (1000 mL) at 78 °C for 3 h with three replicates to remove the decolorization, low-weight molecules. The residue was collected before being added into distilled water (1500 mL) at 100 °C for 3 h to redissolve polysaccharides.…”

Section: Methodsmentioning

confidence: 99%

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Rich d-Fructose-Containing Polysaccharide Isolated from Myxopyrum smilacifolium Roots toward a Superior Antioxidant Biomaterial

Sơn

Nguyen

et al. 2022

ACS Omega

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The presented study attempts to unveil and evaluate the antioxidant activity of a novel heteropolysaccharide separated from the roots of Myxopyrum smilacifolium (denoted as PS-MSR). The molecular weight of PS-MSR is found to be 1.88 × 104 Da and contains two principal sugars, which are d-glucose and d-fructose, in the backbone. Decoding the structure of the obtained PS-MSR sample has disclosed a novel polysaccharide for the first time. Indeed, the PS-MSR is composed of (1 → 3)-linked glucosyl units and (2 → 3)-linked fructosyl units. In addition, the 1D and 2D NMR spectra of the PS-MSR sample display the repeating unit of the isolated polysaccharide, [→3)-α-d-Glcp-(1 → 3)-β-d-Frucf-(2 → 3)-β-d-Frucf-2 → 3)-)-β-d-Frucf-β-(2→] n . Interestingly, the PS-MSR sample exhibits outstanding antioxidant activity, signifying the potential utilization of the explored polysaccharide for antioxidant-based material.

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“…The water-soluble polysaccharides were collected through a two-step extraction, as shown in Scheme . Briefly, the defatted M.…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Rich d-Fructose-Containing Polysaccharide Isolated from Myxopyrum smilacifolium Roots toward a Superior Antioxidant Biomaterial

Sơn

Nguyen

et al. 2022

ACS Omega

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“…Its glucose to mannose molar ratio was 3:2 in the structure. 29 However, such a high temperature facilitates the extraction of the polysaccharide possessing a high molecular mass. Consequently, there is insufficient understanding of the chemical structure and antioxidant activity of O. sobolifera -derived small-molecular-mass polysaccharides.…”

Section: Introductionmentioning

confidence: 99%

“…The molecular mass of the obtained polysaccharide, extracted at a temperature of 100 °C for 3 h and in triplicate, is in the range of ∼2.29 × 10 5 Da. Its glucose to mannose molar ratio was 3:2 in the structure . However, such a high temperature facilitates the extraction of the polysaccharide possessing a high molecular mass.…”

Section: Introductionmentioning

confidence: 99%

Structural Characterization of Mannoglucan Isolated from Ophiocordyceps sobolifera and Its Antioxidant Activities

Tran

et al. 2022

ACS Omega

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A novel polysaccharide structure (PS-T80) was collected from Ophiocordyceps sobolifera biomass and characterized via a combination of chemical and spectral analyses. Employing high-performance gel permeation chromatography (HPGPC), the average molecular weight is proven to be 7.4 × 10 4 Da. Furthermore, a sugar composition analysis of the obtained polysaccharide suggests two main sugars, β- d -glucose and α- d -mannose, at a molar ratio of 2:1, respectively, in the backbone. The structure analysis unveils that PS-T80 is a mannoglucan, possessing the repeating unit of [→3)-β- d -Glcp-(1 → 3)-α- d -Manp-(1 → 3)-β- d -Glcp-(1→] n . Such a configuration could be considered a novel polysaccharide. Impressively, in vitro antioxidant tests revealed that PS-T80 has a promising antioxidant activity. These results demonstrate that the obtained PS is a potential bioactive material for biomedical applications.

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Unfolding the structure of polysaccharide isolated from Myxopyrum smilacifolium leaves toward a robust antioxidant

Nguyen

Sơn

et al. 2023

Bioactive Carbohydrates and Dietary Fibre

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Chemical structure of a novel heteroglycan polysaccharide isolated from the biomass of Ophiocordyceps Sobolifera

Cited by 9 publications

References 66 publications

Rich d-Fructose-Containing Polysaccharide Isolated from Myxopyrum smilacifolium Roots toward a Superior Antioxidant Biomaterial

Rich d-Fructose-Containing Polysaccharide Isolated from Myxopyrum smilacifolium Roots toward a Superior Antioxidant Biomaterial

Structural Characterization of Mannoglucan Isolated from Ophiocordyceps sobolifera and Its Antioxidant Activities

Unfolding the structure of polysaccharide isolated from Myxopyrum smilacifolium leaves toward a robust antioxidant

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