“…Many thiazole derivatives show various biological activities such as antibacterial, antifungal, antiallergic and anti-HIV properties [2][3][4]. Convenient syntheses of thiazole derivatives involve reactions of aryl ketones with a N,N-diformylaminomethyl substituent in chloroform in the presence of excess triethylamine and phosphorus pentasul de at 60°C [5], of isocyanides containing active methylene with carbodithioates in dimethylformamide in the presence of excess sodium hydride at room temperature [6], of thioureas with propargyl bromides in dimethylformamide in the presence of potassium carbonate under microwave condition [7], of N-bromosuccinimide with β-keto esters in the presence of thiourea in aqueous acetone at 50°C [8], of aldehydes with 2-amino(thio)phenols and aldehydes in aqueous ethanol in the presence of using samarium tri uoromethanesulfonate 55°C [9], and of β-diketones with 2-aminothiophenols in the presence of a Brønsted acid as a catalyst [10]. The asymmetric unit of the title crystal structure comprises one molecule of C 28 H 20 FN 3 OS (cf.…”