ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL STUDY OF 2‐AMINOIMIDAZOLES AND 3‐AMINO‐S‐TRIAZOLES

Abstract

Propargylamin (II) reagiert mit den Isothioharnstoffen (I) unter Tos‐OH‐Katalyse zu den instabilen Guanidinen (III), die zu den Aminoimidazolen (IV) cyclisieren.

A Convenient Synthesis of Highly Substituted 3-N,N-Dialkylamino-1,2,4-triazoles

“…8 The advantages of using the acid chloride should be qualified by the low yields sometimes experienced with this technique. 9 The synthetic strategy most commonly employed for the preparation of the molecules under discussion was introduced by Maffrand and co-workers 10 and involves the condensation of an S-methylisothiourea with an acyl hydrazine (Scheme 1).…”