ChemInform Abstract: Synthesis of Substituted 1,2,4‐Oxadiazoles, Isoxazoles, and 1,2,4‐Triazoles from Nitrile Oxides as well as from Azomethinimines.

Abstract

Treating the hydroximoyl chlorides (I) with bases in dilute solution gives their nitrile oxides which in situ react with dialkylcyanamides, e.g. (II), yielding 1,2,4‐oxadiazoles, e.g. (III).