ChemInform Abstract: Transformed Steroids. Part 166. 17α‐Thioanalogues of 21‐Hydroxy‐20‐ketosteroid 16,17‐Acetonides (I), (II): Synthesis and Biological Activity.

Steroids: reactions and partial synthesis

“…Photodeconjugation of the oxime (225) involves an intramolecular stereospecific transfer of the hydroxyimino hydrogen atom.lo2 The product (226) is formed in 69-75 O/ O yield in aprotic as well as protic solvents. Thus the presence of the methyl group at C-1 prevents the ring opening to the nitrile oxide and the subsequent isoxazole formation observed earlier…”