Chemistry and Technology of Evanescent Wave Biosensors

Thompson, Richard B.; Ligler, Frances S.

doi:10.1007/978-1-4612-0483-1_4

Cited by 23 publications

(10 citation statements)

References 48 publications

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“…3. Proper adjustment of the refractive indexes of the waveguide and the surrounding media enables the performance of surface-specific spectroscopy [35,36]; this is difficult to apply in condensed media. 4.…”

Section: Advantages and Disadvantages Of Fiber-optic Sensorsmentioning

confidence: 99%

Fiber-optic biosensors – an overview

2002

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This article reviews progress and developments during the past five years in the field of optical fiber biosensors. Because of the expense and time constraints associated with modern laboratory analysis, there is a growing need for real-time, low-cost technology that can be used industrially, environmentally, and clinically, and to monitor food processing. Miniaturization, integrated systems, and multianalyte determination have become key aspects of sensor development and efforts in this direction will also be discussed, with some pointers to likely directions of future research in the area. The review will provide information about the analytical characteristics and applications of fiber-optic biosensors classified depending on the biorecognition element employed - enzymes, whole cells, antibodies, nucleic acids, and biomimetic polymers.

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Section: Advantages and Disadvantages Of Fiber-optic Sensorsmentioning

confidence: 99%

Fiber-optic biosensors – an overview

2002

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“…The same general approach is also Figure 33. General configuration of an optical detection system for a fiber-optical sensor a) Source; b) Beam splitter; c) Fiber; d) Sensing area; e) Detector The excitation system consists of a xenon or tungsten lamp together with a monochromator or optical filter, an LED, or a laser, whereas the light detection system might be a monochromator or filter with a photomultiplier or photodiode applicable to immobilized antibodies and tagged antigens [169].…”

Section: Fiber-optical Sensorsmentioning

confidence: 99%

Chemical and Biochemical Sensors

Cammann¹,

Roß²,

Katerkamp³

et al. 2001

Ullmann's Encyclopedia of Industrial Chemistry

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The article contains sections titled: 1. Introduction to the Field of Sensors and Actuators 2. Chemical Sensors 2.1. Introduction 2.2. Molecular Recognition Processes and Corresponding Selectivities 2.2.1. Catalytic Processes in Calorimetric Devices 2.2.2. Reactions at Semiconductor Surfaces and Interfaces Influencing Surface or Bulk Conductivities 2.2.3. Selective Ion Conductivities in Solid‐State Materials 2.2.4. Selective Adsorption ‐ Distribution and Supramolecular Chemistry at Interfaces 2.2.5. Selective Charge‐Transfer Processes at Ion‐Selective Electrodes (Potentiometry) 2.2.6. Selective Electrochemical Reactions at Working Electrodes (Voltammetry and Amperometry) 2.2.7. Molecular Recognition Processes Based on Molecular Biological Principles 2.3. Transducers for Molecular Recognition: Processes and Sensitivities 2.3.1. Electrochemical Sensors 2.3.1.1. Self‐Indicating Potentiometric Electrodes 2.3.1.2. Voltammetric and Amperometric Cells 2.3.1.3. Conductance Devices 2.3.1.4. Ion‐Selective Field‐Effect Transistors (ISFETs) 2.3.2. Optical Sensors 2.3.2.1. Fiber‐Optical Sensors 2.3.2.2. Integrated Optical Chemical and Biochemical Sensors 2.3.2.3. Surface Plasmon Resonance 2.3.2.4. Reflectometric Interference Spectroscopy 2.3.3. Mass‐Sensitive Devices 2.3.3.1. Introduction 2.3.3.2. Fundamental Principles and Basic Types of Transducers 2.3.3.3. Theoretical Background 2.3.3.4. Technical Considerations 2.3.3.5. Specific Applications 2.3.3.6. Conclusions and Outlook 2.3.4. Calorimetric Devices 2.4. Problems Associated with Chemical Sensors 2.5. Multisensor Arrays, Electronic Noses, and Tongues 3. Biochemical Sensors (Biosensors) 3.1. Definitions, General Construction, and Classification 3.2. Biocatalytic (Metabolic) Sensors 3.2.1. Monoenzyme Sensors 3.2.2. Multienzyme Sensors 3.2.3. Enzyme Sensors for Inhibitors ‐ Toxic Effect Sensors 3.2.4. Biosensors Utilizing Intact Biological Receptors 3.3. Affinity Sensors ‐ Immuno‐Probes 3.3.1. Direct‐Sensing Immuno‐Probes without Marker Molecules 3.3.2. Indirect‐Sensing Immuno‐Probes using Marker Molecules 3.4. Whole‐Cell Biosensors 3.5. Problems and Future Prospects 4. Actuators and Instrumentation 5. Future Trends and Outlook

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“…A useful property of the evanescent wave is that its intensity decreases exponentially with distance from the interface between the fiber and the surrounding material (Thompson and Ligler, 1991). When this occurs essentially all of the light that is applied (launched) to the surface is propagated through the fiber.…”

Section: Fiber Optic Devicesmentioning

confidence: 99%

Emerging Technologies for Mycotoxin Detection

Maragos

2004

Journal of Toxicology: Toxin Reviews

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Chemistry and Technology of Evanescent Wave Biosensors

Cited by 23 publications

References 48 publications

Fiber-optic biosensors – an overview

Fiber-optic biosensors – an overview

Chemical and Biochemical Sensors

Emerging Technologies for Mycotoxin Detection

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