Chemokine and Fgf signalling act as opposing guidance cues in formation of the lateral line primordium

Breau, Marie Anne; Wilson, Duncan; Wilkinson, David G.; Xu, Qiling

doi:10.1242/dev.080275

Cited by 23 publications

(21 citation statements)

References 35 publications

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“…This study clearly demonstrates that epibranchial placodal cells migrate (Lassiter et al, 2009) (Breau et al, 2012). Anterior to the left.…”

Section: Cellular Interactions and Molecular Cues Interaction Betweensupporting

confidence: 53%

“…We further showed that this retention is mediated by Fgf chemotactic ligands secreted by the primordium (Fig. 4) (Breau et al, 2012). This mechanism facilitates the coalescence of the placode into a compact group of migrating cells.…”

Section: Fgf Signallingmentioning

confidence: 59%

“…This placode, found in aquatic vertebrates, generates a group of cells (the primordium) which migrates from head to tail along the somitic myoseptum to deposit superficial sensory organs called neuromasts (Aman and Piotrowski, 2011;Ma and Raible, 2009). We observed (Breau et al, 2012) that prior to the onset of this antero-posterior migration, the compact state of the primordium is not established, as isolated cells with lateral line placode identity are present ahead of the primordium. Although these isolated cells appear static, we showed that they are actively maintained in position by a chemotactic mechanism, in the absence of which they migrate away from the primordium (Fig.…”

Section: Cell Retentionmentioning

confidence: 79%

“…4). This cell retention facilitates the fusion of the isolated placodal cells with the primordium as it advances (Breau et al, 2012). In a similar way, trigeminal neuroblasts also appear to be actively retained by chemotactism at the site of ganglion aggregation in zebrafish (Knaut et al, 2005).…”

Section: Cell Retentionmentioning

confidence: 84%

“…The formation of segregated placode primordia correlates in time with upregulation of transcription factors specifically expressed in individual or groups of placodes Pieper et al, 2011;Schlosser, 2010;Streit, 2008). Pax2 and Pax8, expressed in the otic and epibranchial placode progenitors (and in lateral line placodes in fish and amphibians), show saltand-pepper expression in chick (Groves and Bronner-Fraser, 2000;Streit, 2002), Xenopus (Pieper et al, 2011;Schlosser and Ahrens, 2004), zebrafish (Bhat et al, 2013;Bhat and Riley, 2011;Hans and Westerfield, 2007;McCarroll et al, 2012; Kozlowski et al, 1997;Bhattacharyya and Bronner, 2013;Breau et al, 2012;Dutta et al, 2005;Harden et al, 2012;Knaut et al, 2005;Kwan et al, 2011;Pieper et al, 2011;Streit, 2002;Whitlock and Westerfield, 2000;Xu et al, 2008) al., 2012) and mice (Ohyama and Groves, 2004). Pax6, a transcription factor expressed in the lens placode, exhibit mosaic expression in zebrafish (Dutta et al, 2005;Hans and Westerfield, 2007).…”

Section: Confrontation Of the Models With Experimental Evidencementioning

confidence: 99%

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Mechanisms of cranial placode assembly

Breau¹,

Schneider‐Maunoury²

2014

Int. J. Dev. Biol.

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Cranial placodes are transient ectodermal structures contributing to the paired sensory organs and ganglia of the vertebrate head. Placode progenitors are initially spread and intermixed within a continuous embryonic territory surrounding the anterior neural plate, the so-called panplacodal region, which progressively breaks into distinct and compact placodal structures. The mechanisms driving the formation of these discrete placodes from the initial scattered distribution of their progenitors are poorly understood, and the implication of cell fate changes, local sorting out or massive cell movements is still a matter of debate. Here, we discuss different models that could account for placode assembly and review recent studies unraveling novel cellular and molecular aspects of this key event in the construction of the vertebrate head.

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“…This study clearly demonstrates that epibranchial placodal cells migrate (Lassiter et al, 2009) (Breau et al, 2012). Anterior to the left.…”

Section: Cellular Interactions and Molecular Cues Interaction Betweensupporting

confidence: 53%

Section: Fgf Signallingmentioning

confidence: 59%

Section: Cell Retentionmentioning

confidence: 79%

Section: Cell Retentionmentioning

confidence: 84%

Section: Confrontation Of the Models With Experimental Evidencementioning

confidence: 99%

See 3 more Smart Citations

Mechanisms of cranial placode assembly

Breau¹,

Schneider‐Maunoury²

2014

Int. J. Dev. Biol.

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Ear and Lateral Line of Vertebrates: Organisation and Development

Harding

McCarroll

McGraw

et al. 2013

Encyclopedia of Life Sciences

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In vertebrates, perception of movement and sound is accomplished by the lateral line and inner ear sensory systems. These systems sense reverberations, movement and acceleration by transducing mechanical stimuli from the environment into electrical signals by means of mechanosensory hair cells. Vestibular and auditory hair cells have associated sensory neurons that transmit these signals from the periphery to the central nervous system. During development, cranial sensory systems arise from an initially homogeneous population of cells that ultimately give rise to discrete sensory structures. Although the demands for auditory and vestibular sensation differ between species and environments, vertebrates use common cell types, genetic programmes and molecules to achieve the development of these mechanosensory organs. In this article, the structure and function of the mechanosensory hair cells, lateral line and inner ear and how these systems develop across species are discussed, and as well as the innervation of these systems. Key Concepts: The vertebrate inner ear is composed of both auditory and vestibular components. Both the lateral line and the inner ear are derived from embryonic structures known as cranial placodes. All cranial placodes originate from a homogenous group of cells known as the preplacodal ectoderm. Hair cells are structurally and functionally similar in both auditory and lateral line systems. The adult lateral line mediates sensation of movement in the aquatic environment of fishes and frogs. Embryonic posterior lateral line development is accomplished by the pre‐patterned posterior lateral line primordium. The lateral line is an experimentally accessible model for studying mechanosensory system development and biology.

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Collective cell migration of epithelial and mesenchymal cells

Théveneau

Mayor

2013

Cell. Mol. Life Sci.

144

109

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Directional cell migration is required for proper embryogenesis, immunity, and healing, and its underpinning regulatory mechanisms are often hijacked during diseases such as chronic inflammations and cancer metastasis. Studies on migratory epithelial tissues have revealed that cells can move as a collective group with shared responsibilities. First thought to be restricted to proper epithelial cell types able to maintain stable cell-cell junctions, the field of collective cell migration is now widening to include cooperative behavior of mesenchymal cells. In this review, we give an overview of the mechanisms driving collective cell migration in epithelial tissues and discuss how mesenchymal cells can cooperate to behave as a collective in the absence of bona fide cell-cell adhesions.

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Chemokine and Fgf signalling act as opposing guidance cues in formation of the lateral line primordium

Cited by 23 publications

References 35 publications

Mechanisms of cranial placode assembly

Mechanisms of cranial placode assembly

Ear and Lateral Line of Vertebrates: Organisation and Development

Collective cell migration of epithelial and mesenchymal cells

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