“…Engineered nanomaterials can help protect the active ingredients from direct contact with blood by means of carrier adsorption, encapsulation, or conjugation, leading to increased drug efficacy 119 . Nano-formulated active ingredients of CHMs tend to enhance the retention, accumulation, and penetration of active ingredients in tumor sites, in addition to facilitating a controlled release of active ingredients in the tumor extracellular matrix or tumor cells.…”
Section: Nano-formulated Delivery Of Active Ingredients From Chms For...mentioning
“…Engineered nanomaterials can help protect the active ingredients from direct contact with blood by means of carrier adsorption, encapsulation, or conjugation, leading to increased drug efficacy 119 . Nano-formulated active ingredients of CHMs tend to enhance the retention, accumulation, and penetration of active ingredients in tumor sites, in addition to facilitating a controlled release of active ingredients in the tumor extracellular matrix or tumor cells.…”
Section: Nano-formulated Delivery Of Active Ingredients From Chms For...mentioning
“…Finally, due to its ability to exist in multiple oxidation states, 99m Tc exhibits a wide range of chemical properties. 30,31 This fact provides the possibility of creating a broad spectrum of complexes with distinct properties, which is a notable benefit in the advancement of radiopharmaceuticals. The present study suggests that utilizing 99m Tc as a radionuclide for the purpose of labeling nanoparticles that exhibit glucose on their surface may serve as a promising substitute for 18 F-FDG and PET.…”
The demand for tailored, disease-adapted, and easily accessible radiopharmaceuticals is one of the most persistent in nuclear imaging precision medicine. The aim of this work was to develop two multimodal...
“…[1][2][3][4] High doses of chemotherapy drugs will damage normal tissues and organs. [5][6][7] Tumor cells rely on nutrients transported by blood vessels to proliferate. [8][9][10] When the nutrient transport channel is blocked, tumor cells will starve to death, thus achieving the effect of inhibiting tumor growth.…”
The goal of inhibiting tumor growth can be achieved by cutting off the supply of nutrients in the blood vessels of the tumor site, but how to effectively, accurately and...
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