Childhood carcinoid tumors: The St Jude Children's Research Hospital experience

Spunt, Sheri L.; Pratt, Charles B.; Rao, Bhaskar N.; Pritchard, Michele; Jenkins, Jesse J.; Hill, Deirdre A.; Cain, Alvida M.; Pappo, Alberto S.

doi:10.1053/jpsu.2000.9297

Cited by 90 publications

(64 citation statements)

References 15 publications

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“…Frequently this tumor occurs in girls aged 12 to 13 yrs. Similar to other studies, we detected a slight female preponderance [6,7]. Furthermore, the median age at diagnosis in the present study was 10.75 y, which is lower than the reported by most authors [8,11].…”

Section: Discussionsupporting

confidence: 88%

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Carcinoid Tumors of the Appendix – Last Decade Experience

Anastasiadis

Kepertis

Lampropoulos

et al. 2014

JCDR

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Section: Discussionsupporting

confidence: 88%

“…In pediatric patients, the rate is 0,08-0.5% [2,[3][4][5][6][7]. The overall incidence of carcinoid tumors in surgical specimens has been estimated to 1 to 2 cases per 1000 appendectomies.…”

Section: Introductionmentioning

confidence: 99%

Carcinoid Tumors of the Appendix – Last Decade Experience

Anastasiadis

Kepertis

Lampropoulos

et al. 2014

JCDR

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“…Moertel et al [20] found no recurrences when analyzing their entire patient data in the group up to 20 years. We performed a MEDLINE search summarizing additional series [21][22][23][24][25][26][27][28][29][30] and did not find any documented case of a childhood solitary enterochromaffin cell AC with completely resected PT having metastases beyond LNM or relapsing during later life (Table 1).…”

Section: E2mentioning

confidence: 99%

Appendiceal carcinoid tumor with lymph node metastasis in a child: case report and review of the literature

Cernaianu¹,

Tannapfel²,

Nounla³

et al. 2010

Journal of Pediatric Surgery

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“…Neuroendocrine epithelial neoplasms are rarely encountered in children below the age of 10 years [1][2][3][4][5]. The youngest reported patient was a 6-year-old child with appendiceal carcinoid [2].…”

Section: Introductionmentioning

confidence: 99%

CD99-positive large cell neuroendocrine carcinoma with rearranged EWSR1 gene in an infant: a case of prognostically favorable tumor

et al. 2010

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The first case of large cell neuroendocrine carcinoma arising in an infant is presented. The tumor arose at the anal verge of a 1-year-old girl. The diagnosis of this CD99-positive tumor was supported by expression of epithelial (keratins, EMA, and Ep-CAM) and neuroendocrine (chromogranin A, synaptophysin, and neuron-specific enolase) markers and absence of immunoreactivity for Fli-1. No fusion of EWSR1 with FLI-1 or ERG was detected by polymerase chain reaction. However, the split of the EWSR1 gene was demonstrated by fluorescence in situ hybridization. This case adds to the few epithelial tumors in which an EWSR1 rearrangement was demonstrated. Because the tumor was initially misclassified as an extraskeletal Ewing's sarcoma, the patient was treated according to the Ewing's sarcoma treatment protocol. She remains free of tumor 8 years after initial diagnosis.

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Childhood carcinoid tumors: The St Jude Children's Research Hospital experience

Cited by 90 publications

References 15 publications

Carcinoid Tumors of the Appendix – Last Decade Experience

Carcinoid Tumors of the Appendix – Last Decade Experience

Appendiceal carcinoid tumor with lymph node metastasis in a child: case report and review of the literature

CD99-positive large cell neuroendocrine carcinoma with rearranged EWSR1 gene in an infant: a case of prognostically favorable tumor

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