Childhood Sudden Death Secondary to Accidental Aspiration of Black Pepper

Sheahan, Kieran; Page, Denise; Kemper, Thomas; Suarez, Ronald V.

doi:10.1097/00000433-198803000-00014

Cited by 10 publications

(4 citation statements)

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“…Severe bleeding was observed in one subject after intake of black pepper. Several cases of fatal pepper administration have been reported in the literature 53, 54. Mechanical obstruction and mucosal oedema were identified as mechanisms of death 54.…”

Section: Alkaloids Derived From Lysinementioning

confidence: 99%

Alkaloids in the human food chain – Natural occurrence and possible adverse effects

Koleva

Beek

Soffers

et al. 2011

Molecular Nutrition Food Res

162

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Alkaloid-containing plants are an intrinsic part of the regular Western diet. The present paper summarizes the occurrence of alkaloids in the food chain, their mode of action and possible adverse effects including a safety assessment. Pyrrolizidine alkaloids are a reason for concern because of their bioactivation to reactive alkylating intermediates. Several quinolizidine alkaloids, β-carboline alkaloids, ergot alkaloids and steroid alkaloids are active without bioactivation and mostly act as neurotoxins. Regulatory agencies are aware of the risks and have taken or are considering appropriate regulatory actions for most alkaloids. These vary from setting limits for the presence of a compound in feed, foods and beverages, trying to define safe upper limits, advising on a strategy aiming at restrictions in use, informing the public to be cautious or taking specific plant varieties from the market. For some alkaloids known to be present in the modern food chain, e.g., piperine, nicotine, theobromine, theophylline and tropane alkaloids risks coming from the human food chain are considered to be low if not negligible. Remarkably, for many alkaloids that are known constituents of the modern food chain and of possible concern, tolerable daily intake values have so far not been defined.

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Section: Alkaloids Derived From Lysinementioning

confidence: 99%

Alkaloids in the human food chain – Natural occurrence and possible adverse effects

Koleva

Beek

Soffers

et al. 2011

Molecular Nutrition Food Res

162

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“…44 The child died 4 days later when respiratory support was withdrawn. The aspiration of black pepper by a child with a history of pica resulted in respiratory distress, asphyxia, and cardiopulmonary arrest.…”

Section: Black Peppermentioning

confidence: 99%

Pepper and Capsaicin (CapsicumandPiperSpecies)

Barceloux

Faact²,

Facmt³

2008

Medical Toxicology of Natural Substances

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“…Side effects include burning aftertaste, redness of eyes, and swelling of eyelids 45 . Death has been reported with aspiration of a large amount of pepper 45‐46 …”

Section: Black Peppermentioning

confidence: 99%

Nutraceuticals: Potential Roles and Potential Risks for Pain Management

Kaye

Hegazi

et al. 2002

Pain Practice

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Over the past 2 decades, the world health market has been flooded with over the counter herbal products, also known as nutraceuticals. Although many of these products are neither recommended nor prescribed by conventional medical practitioners, an increasing number of people are taking these products on a daily basis. A recent survey at Texas Tech University School of Medicine in Lubbock, Texas concluded that 32% of patients scheduled for elective surgery or pain procedures were taking one or more herbal supplements; however, 70% did not disclose these during a routine anesthetic assessment.(1) Pain physicians are also increasingly needed in the care of these patients. As many of these agents carry a potential to cause bleeding problems, we have reviewed here briefly, the basic mechanisms of coagulation and correlated the role of commonly used herbs known to possess side effects, which can cause excessive bleeding. In addition, we have reviewed a number of potential useful herbal derived agents for pain management.

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Childhood Sudden Death Secondary to Accidental Aspiration of Black Pepper

Cited by 10 publications

References 0 publications

Alkaloids in the human food chain – Natural occurrence and possible adverse effects

Alkaloids in the human food chain – Natural occurrence and possible adverse effects

Pepper and Capsaicin (CapsicumandPiperSpecies)

Nutraceuticals: Potential Roles and Potential Risks for Pain Management

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