Children's Depression Rating Scale--Revised

Poznanski, Elva O.; Grossman, Janet; Buchsbaum, Yael; Banegas, Marta; Freeman, Linda; Gibbons, Robert D.

doi:10.1037/t55280-000

Cited by 491 publications

(660 citation statements)

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“…The psychometric properties of the SCARED have been examined in two independent samples, with similar findings of strong internal consistency for total score, the variable used in the current study (Birmaher et al 1999). Clinicians who provided treatment rated depressive symptoms using the Child Depression Rating Scale-Revised (CDRS-R) (Poznanski and Mokros 1996), a 17-item measure based on an interview with the participant and parent.…”

Section: Methodsmentioning

confidence: 99%

Real-World Affect and Social Context as Predictors of Treatment Response in Child and Adolescent Depression and Anxiety: An Ecological Momentary Assessment Study

Forbes

Stepp

Dahl

et al. 2012

Journal of Child and Adolescent Psychopharmacology

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Objective: Response to treatment in child and adolescent affective disorders is variable, with limited ability of any one treatment to improve outcome across patients. Unfortunately, we know little about the factors that explain this variability in treatment response. Individual differences in the social and affective dynamics of daily life could help to elucidate the characteristics of youth who respond to treatment. Methods: We used ecological momentary assessment of negative affect, positive affect, and companions in natural settings over 4 days in a sample of young people with depressive and anxiety disorders who participated in an 8-week open trial of cognitive behavioral therapy (CBT), selective serotonin reuptake inhibitors (SSRIs), or a combination of the two. Clinicians rated participants' clinical severity at five time points, and participants reported their symptoms before and after treatment. Latent growth curve models were used to predict rate of change in clinical severity from pretreatment affect in natural settings. Results: Participants with high positive affect (PA), low negative affect (NA), and a high PA:NA ratio at baseline had lower severity, depressive symptoms, and anxiety symptoms at the end of treatment. Lower posttreatment symptoms were associated with spending more time with fathers and less time with peers before treatment. Although baseline affect was not associated with initial symptom severity, high NA and low PA:NA at baseline were related to slower rate of decline of severity during treatment. When baseline symptoms were included in models, NA and PA:NA predicted rate of decline in severity during treatment, whereas self-reported depressive and anxiety symptoms at baseline did not. Conclusion: A more typical profile of baseline affective functioning in natural settings-that is, lower NA and higher PAand time with fathers, could provide a foundation for treatment response in children and adolescents. Affective and social dynamics in natural settings could ultimately help investigate which young people might benefit from current treatments.

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Section: Methodsmentioning

confidence: 99%

Real-World Affect and Social Context as Predictors of Treatment Response in Child and Adolescent Depression and Anxiety: An Ecological Momentary Assessment Study

Forbes

Stepp

Dahl

et al. 2012

Journal of Child and Adolescent Psychopharmacology

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“…Anxiety symptoms were assessed with the Hamilton Anxiety Rating Scale and the Revised Children's Manifest Anxiety Scale for adults and children, respectively. Depression symptoms were assessed with the Hamilton Rating Scale for Depression (Hamilton, 1960) and the Children's Depression Rating Scale-Revised (Poznanski and Mokros, 1996) for adults and children, respectively. Because the assessment measures for depressive and anxiety symptoms differed in adults vs children, symptom severity scores were transformed into z-scores.…”

Section: Exploratory Analysesmentioning

confidence: 99%

Increased Default Mode Network Connectivity in Individuals at High Familial Risk for Depression

Posner

Cha

Wang

et al. 2015

Neuropsychopharmacol

117

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Research into the pathophysiology of major depressive disorder (MDD) has focused largely on individuals already affected by MDD. Studies have thus been limited in their ability to disentangle effects that arise as a result of MDD from precursors of the disorder. By studying individuals at high familial risk for MDD, we aimed to identify potential biomarkers indexing risk for developing MDD, a critical step toward advancing prevention and early intervention. Using resting-state functional connectivity MRI (rs-fcMRI) and diffusion MRI (tractography), we examined connectivity within the default mode network (DMN) and between the DMN and the central executive network (CEN) in 111 individuals, aged 11-60 years, at high and low familial risk for depression. Study participants were part of a threegeneration longitudinal, cohort study of familial depression. Based on rs-fcMRI, individuals at high vs low familial risk for depression showed increased DMN connectivity, as well as decreased DMN-CEN-negative connectivity. These findings remained significant after excluding individuals with a current or lifetime history of depression. Diffusion MRI measures based on tractography supported the findings of decreased DMN-CEN-negative connectivity. Path analyses indicated that decreased DMN-CEN-negative connectivity mediated a relationship between familial risk and a neuropsychological measure of impulsivity. Our findings suggest that DMN and DMN-CEN connectivity differ in those at high vs low risk for depression and thus suggest potential biomarkers for identifying individuals at risk for developing MDD.

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“…Primary outcome measurements were the Clinical Global Improvement (CGI) improvement score (CGI р 2) and the Children's Depression Rating Scale, Revised (CDRS-R) (Poznanski et al 1985). Following randomization, each patient was given one capsule of placebo or 20 mg of fluoxetine every morning and seen weekly for eight consecutive weeks.…”

Section: Methodsmentioning

confidence: 99%

Clinician, Parent, and Child Prediction of Medication or Placebo in Double-Blind Depression Study

Hughes

Kowatch

Weinberg

et al. 2000

Neuropsychopharmacology

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To evaluate how well a blind is maintained in a doubleblind study. Clinicians ( n ϭ 66), parents ( n ϭ 62), and depressed child/adolescent subjects ( n ϭ 62) predicted whether the patient had been on either placebo In a randomized, double blind study of 96 patients, fluoxetine was found to be superior to placebo in the acute phase treatment of major depressive disorder in child and adolescent outpatients (Emslie et al. 1997). One issue of concern to double blind studies is how well the blind is maintained over the course of the study as the investigators become more familiar with the treatment outcomes. First, does the clinician accurately predict whether a patient received either drug or placebo treatment? Second, how well do the subjects or their parents predict which treatment they received following eight weeks of treatment? And finally, what is the relationship of the clinical response to treatment and the prediction of whether they received medication or placebo? We report here the findings of a study to evaluate these predictions and to test the integrity of the double-blind study. MATERIALS AND METHODSNinety-six child and adolescent outpatients (aged 7-17) with nonpsychotic major depressive disorder were randomized to 20 mg of fluoxetine or placebo (Emslie et al. 1997). All subjects provided written assent, and their parent(s) written consent to participate in the study. The research protocol was approved by the University IRB committee. They were seen weekly for eight consecutive weeks preceded by three evaluation visits and a one-week, single blind placebo run-in (Rintlemann et al. 1996). Subjects were administered a semistructured DSM-III-R-based diagnostic interview (Welner et al.

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Children's Depression Rating Scale--Revised

Cited by 491 publications

References 0 publications

Real-World Affect and Social Context as Predictors of Treatment Response in Child and Adolescent Depression and Anxiety: An Ecological Momentary Assessment Study

Real-World Affect and Social Context as Predictors of Treatment Response in Child and Adolescent Depression and Anxiety: An Ecological Momentary Assessment Study

Increased Default Mode Network Connectivity in Individuals at High Familial Risk for Depression

Clinician, Parent, and Child Prediction of Medication or Placebo in Double-Blind Depression Study

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