Chrono-coherent imaging for medicine

Abstract

Imaging inside the body with optical wavelengths encounters problems due to light scattering of tissues and other optical distortions. A description is given of chrono-coherent imaging (CCI), a new method for imaging with visible and near-infrared light that uses coherent image formation and subpicosecond timing to remove the time-delayed scattered light. With CCI it is possible to form images in the presence of the overwhelming amount of scattered light that blocks conventional image formation. The coherent image formation process allows the use of long-duration, high-total-energy, and modest-peak-power pulses to overcome scattering losses. CCI is an extension of light-in-flight holography, which combines the properties of short-duration pulses and hologaphy for various measurements of objects and optical wavefronts.

Depth-resolved holography through turbid media using photorefraction

“…Time-gated holography, known as light-in-flight holography, was first proposed by Abramson [15] and later applied to biomedical imaging by Spears et al [21]. We first demonstrated the use of light-in-flight holography to obtain depthresolved images through 8 mfp of scattering medium, with a depth resolution of 2 mm [22].…”

Overview and applications of Grating Light Valve™ based image acquisition and projection display system

“…The -coherent imaging [8] used for basis to implement the optical medical applications. Our novel g of the Grating Light Valve based acquisition unit, and the ogether provide a solid, stable, for creating real-time, highr a wide variety of display III.…”

Time-gated viewing studies on tissuelike phantoms

“…One technique is based on holographic detection, in which the first transmitted photons are gated out by the use of the coherent interference between this light and a gate pulse on a holographic plate. 7,8 This technique implies, as a result of the demand of coherence, that the first light exiting the tissue is coherent with the laser pulse. Light delayed because of multiple scattering in the tissue has lost the coherence and thus contributes to an undesirable background.…”