2020
DOI: 10.1101/2020.07.31.230821
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Circumventing the optical diffraction limit with customized speckles

Abstract: Speckle patterns have been widely used in imaging techniques such as ghost imaging, dynamic speckle illumination microscopy, structured illumination microscopy, and photoacoustic fluctuation imaging. Recent advances in the ability to control the statistical properties of speckles has enabled the customization of speckle patterns for specific imaging applications. In this work, we design and create special speckle patterns for parallelized nonlinear pattern-illumination microscopy based on fluorescence photosw… Show more

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Cited by 4 publications
(4 citation statements)
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“…The key advantage of our concept is that it renders possible any form of widefield microscopy at the tip of a hair thin strand of MMF. This includes localisation-based super-resolution imaging [22,23], along with other emerging forms of parallelised super-resolution microscopy [71], structured illumination microscopy [72] and singleobjective light sheet microscopy [73]. Single-shot widefield imaging at any distance beyond the distal end of a short length of MMF also becomes possible.…”
Section: Discussionmentioning
confidence: 99%
“…The key advantage of our concept is that it renders possible any form of widefield microscopy at the tip of a hair thin strand of MMF. This includes localisation-based super-resolution imaging [22,23], along with other emerging forms of parallelised super-resolution microscopy [71], structured illumination microscopy [72] and singleobjective light sheet microscopy [73]. Single-shot widefield imaging at any distance beyond the distal end of a short length of MMF also becomes possible.…”
Section: Discussionmentioning
confidence: 99%
“…The key advantage of our concept is that it renders possible any form of wide-field microscopy at the tip of a hair thin strand of MMF. This includes localisation-based superresolution imaging [18,19], along with other emerging forms of parallelised super-resolution microscopy [62], and structured illumination microscopy [63]. Single-shot wide-field imaging at any distance beyond the distal end of a short length of MMF also becomes possible.…”
Section: Discussionmentioning
confidence: 99%
“…These special characteristics give speckle patterns with unpredicted potential in many areas [1]. It has been widely used in measurement, bioimaging, and metrology [2][3][4]. Owing to the strong wavelength dependent characteristic of the speckle patterns, it is also employed as the carrier of light wavelengths.…”
Section: Introductionmentioning
confidence: 99%