Citrulline malate supplementation might potentiate post-exercise hypotension in hypertensives: A 24-hour analysis

Casonatto, Juliano; Cavalari, João Vagner; Goessler, Karla Fabiana; Christófaro, Diego Giulliano Destro; Polito, Marcos Doederlein; Enokida, Daniel Massaharu; Grandolfi, Kamila

doi:10.1016/j.scispo.2019.03.001

Cited by 4 publications

(1 citation statement)

References 49 publications

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“…Later, da Silva et al [81], showed CM supplementation failed to improve the muscle recovery process after a high-intensity RE session in untrained young adult men. Recently, Casonatto et al [82], studied if CM supplementation (6 g) had an impact in the acute post-exercise blood pressure response in hypertensive adults, obtaining a potential positive effect.…”

Section: Studies With Citrulline Malate (Cm)mentioning

confidence: 99%

L-Citrulline: A Non-Essential Amino Acid with Important Roles in Human Health

et al. 2021

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L-Arginine (Arg) has been widely used due to its functional properties as a substrate for nitric oxide (NO) generation. However, L-citrulline (CIT), whose main natural source is watermelon, is a non-essential amino acid but which has important health potential. This review provides a comprehensive approach to different studies of the endogenous synthesis of CIT, metabolism, pharmacokinetics, and pharmacodynamics as well as its ergogenic effect in exercise performance. The novel aspect of this paper focuses on the different effects of CIT, citrulline malate and CIT from natural sources such as watermelon on several topics, including cardiovascular diseases, diabetes, erectile dysfunction, cancer, and exercise performance. CIT from watermelon could be a natural food-sourced substitute for pharmacological products and therefore the consumption of this fruit is promoted.

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Section: Studies With Citrulline Malate (Cm)mentioning

confidence: 99%