Classification of testicular cancer in incidence and mortality statistics

Pike, Malcolm C.; Chilvers, Clair; Bobrow, Lynda G.

doi:10.1038/bjc.1987.159

Cited by 37 publications

(23 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We restricted our study to two 5-y age groups: patients 0-to 4-y-old for childhood cancer and 20-to 24-y-old for cancer in young adulthood. We chose the former age class because childhood testicular cancer rarely occurs after the age of 4 y, and we selected the 20-to 24-y-old age group for comparability purpose because the predominant subtype of testicular cancer in children as well as young adults in their early 20s is nonseminoma (5,9).…”

Section: Populations and Methodsmentioning

confidence: 99%

Time Trends in the Incidence of Testicular Cancer in Childhood and Young Adulthood

Lacerda

Akre

Merletti

et al. 2009

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

Background: There has been a steep increase in the incidence of adult testicular cancer in many populations, but in spite of numerous studies, the etiology of testicular cancer remains elusive. The time trends of childhood testicular tumors are less clear and have been studied in a few populations. To further evaluate whether or not adult and childhood cancers share trend determinants and whether future adult testicular cancer incidences can be predicted through childhood testicular cancer incidences, their rates were compared. Method: Data on testicular cancer incidence in childhood and in young adulthood were extracted from the IARC Cancer Incidence in the Five Continents Data-

show abstract

Section: Populations and Methodsmentioning

confidence: 99%

Time Trends in the Incidence of Testicular Cancer in Childhood and Young Adulthood

Lacerda

Akre

Merletti

et al. 2009

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

show abstract

“…The data set was restricted to the age group 15 to 54 to provide a well-defined grouping for the study of trends of histologic subtypes of germ cell cancers (18).…”

Section: Methodsmentioning

confidence: 99%

“…These and other possibly causal factors, such as low birth weight and low maternal parity, can only account for a small fraction of the total incidence. Previous studies have examined etiologic differences in the two main clinical subentities of testicular germ cell cancer: seminoma and nonseminoma (10,11,(16)(17)(18)(19)(20)(21). Despite well-documented differences in the peak age of incidence (18), most studies have revealed little variation in risk factors between the two subtypes and, where particular associations have been found, they have been inconsistent across studies.…”

Section: Introductionmentioning

confidence: 99%

Do Testicular Seminoma and Nonseminoma Share the Same Etiology? Evidence from an Age-Period-Cohort Analysis of Incidence Trends in Eight European Countries

Bray

Richiardi

Ekbom

et al. 2006

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

The incidence of the two main clinical subentities of testicular germ cell cancer (seminoma and nonseminoma) is increasing throughout Europe. Most studies have revealed little variation in risk factors between the two subtypes. This study compared generation-specific trends in eight European countries, hypothesizing that similar temporal pattern by birth cohort implied that seminoma and nonseminoma had a largely comparable etiology. The results are presented using the age-period-cohort model and the nonidentifiability problem highlighted by partitioning the age, period, and cohort effects in terms of their linear and curvature component parts, assuming a priori that cohort effects predominated. Despite uniform overall increases by calendar period, declining rates of nonseminoma but not pure seminoma were observed in the majority of countries during the 1990s. The subtype trends were, however, largely analogous on a birth cohort scale. Notable observations were a decline in rates of both subtypes among recent birth cohorts in Switzerland and a short-term wartime effect in several countries, involving an attenuation of increasing risk of both subtypes in men born in 1940 to 1945. Departures from the steady increases in testicular cancer over time were likely to occur for nonseminomas some years ahead of seminoma on a period scale. The importance of birth cohort coincided with the view that given a short time interval of susceptibility to exposures earlier in life and a biologically constant time to diagnosis, all temporal changes in rate-limiting exposures should appear as generational effects. Trends in seminoma and nonseminoma conform to largely the same temporal patterns on this scale, implying that they share important etiologic factors. (Cancer Epidemiol Biomarkers Prev 2006;15(4):652 -8)

show abstract

“…The age curve of the disease has two peaks, one in the twenties and one later in life (Clemmesen, 1968), following the relative frequency of different histological types (since teratomas have an earlier peak incidence than the more frequent seminomas, and lymphomas are more frequent at older ages) and possibly reflecting the role of different risk factors (Boyle et al, 1987;Pike et al, 1987). Further, there is evidence that the incidence is now increasing predominantly in young men, and specifically for teratomas (Boyle et al, 1987).…”

mentioning

confidence: 99%