Cleavage and transformation inhibition of extracellular antibiotic resistance genes by graphene oxides with different lateral sizes

Xu, Lei; Zhao, Jian; Liu, Zhuomiao; Wang, Zhenyu; Yu, Kaiqiang; Xing, Baoshan

doi:10.1016/j.scitotenv.2019.133932

Cited by 29 publications

(13 citation statements)

References 39 publications

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“…Considering the carboxyl groups mainly distributed on the edge of GO, the ratios of carboxyl groups increase with the decrease of lateral size of GO, resulting in better aqueous dispersibility relatively [53]. The lateral size of GO can be controlled by the centrifugation [53,56], pH value [54], and ultrasonic treatment with different time [57,58].…”

Section: The Lateral Size Of Gomentioning

confidence: 99%

Water lubrication of graphene oxide-based materials

Xue

Guo

et al. 2021

Friction

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Water is as an economic, eco-friendly, and efficient lubricant that has gained widespread attention for manufacturing. Using graphene oxide (GO)-based materials can improve the lubricant efficacy of water lubrication due to their outstanding mechanical properties, water dispersibility, and broad application scenarios. In this review, we offer a brief introduction about the background of water lubrication and GO. Subsequently, the synthesis, structure, and lubrication theory of GO are analyzed. Particular attention is focused on the relationship between pH, concentration, and lubrication efficacy when discussing the tribology behaviors of pristine GO. By compounding or reacting GO with various modifiers, amounts of GO-composites are synthesized and applied as lubricant additives or into frictional pairs for different usage scenarios. These various strategies of GO-composite generate interesting effects on the tribology behaviors. Several application cases of GO-based materials are described in water lubrication, including metal processing and bio-lubrication. The advantages and drawbacks of GO-composites are then discussed. The development of GO-based materials for water lubrication is described including some challenges.

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Section: The Lateral Size Of Gomentioning

confidence: 99%

Water lubrication of graphene oxide-based materials

Xue

Guo

et al. 2021

Friction

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“…As a new two-dimensional nanomaterial, the effect of graphene oxide (GO) on the removal of antibiotic resistance genes has aroused the interest of researchers. Xu, Yang, et al (2019), Xu, Zhao, et al (2019) studied the transformation inhibition of Kanamycin-resistant gene (aphA)-containing plasmid DNA by GOs. Four GOs with different lateral sizes (1.0, 0.6, 0.17, and 0.08 μm 2 ) can effectively intercalate into plasmid DNA, and GO with smaller lateral size showed better intercalation ability.…”

Section: Othermentioning

confidence: 99%

“…Then, further oxidation is carried out by biological method to improve the mineralization rate of EPs and the quality of effluent (Monteil et al, 2019; Wang, Ying, et al, 2019; Wang, Su, et al, 2019; Wang, Wang, et al, 2019; Wang, Huang, et al, 2019; Wang, Cai, et al, 2019; Wang, Zhu, et al, 2019; Wang, Yin, et al, 2019; Wang, Qian, et al, 2019; Wang, Zhang, et al, 2019; Yan, Sun, et al, 2019; Yan, Yuan, et al, 2019). The combination of various chemical oxidation methods can improve the production efficiency of active groups in the system, leading to the removal rate improvement of EPs (Chen, Zhu, et al, 2019; Chen, Zhang, et al, 2019; Figueredo, Rodríguez, Checa, & Beltran, 2019; Orimolade, Koiki, Peleyeju, & Arotiba, 2019; Sedlazeck et al, 2019; Wang, Ying, et al (2019); ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Wang, Su, et al (2019), Wang, Wang, et al (2019), Wang, Huang, et al (2019), Wang, Cai, et al (2019), Wang, Zhu, et al (2019), Wang, Yin, et al (2019), Wang, Qian, et al (2019), Wang, Zhang, et al (2019); Xu, Yang, et al, 2019; Xu, Zhao, et al, 2019).…”

Section: Combinations Of Treatment Technologiesmentioning

confidence: 99%

Emerging pollutants—Part II: Treatment

Liu

Zhang

Chang

2020

Water Environment Research

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Emerging pollutants (EPs) refer to a class of pollutants, which are emerging in the environment or recently attracted attention. EPs mainly include pharmaceutical and personal care products (PPCPs), endocrine-disrupting chemicals (EDCs), and antibiotic resistance genes (ARGs). EPs have potential threats to human health and ecological environment. In recent years, the continuous detections of EPs in surface and ground water have brought huge challenges to water treatment and also made the treatment of EPs become an international research hotspot. This paper summarizes some research results on EPs treatment published in 2019. This paper may be helpful to understand the current situations and development trends of EP treatment technologies.

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“…49−53 It was reported that small-sized GO nanosheets can easily insert into the base pairs of plasmid DNA and change the double helix structure of DNA through disturbing the base pair stacking mode. 53 Recent experimental evidences indicated that the ARG removal efficiency might be caused by strong binding of GO with DNA through strong electrostatic attraction. 49 Albeit the numerous experimental reports, little is known about the mechanism of interactions between GO and dsDNA which is a determinative factor toward the removal capability of nanomaterials to ARGs.…”

Section: Introductionmentioning

confidence: 99%

“…One distinguished feature of 2D nanomaterials is the large surface which can absorb variety of molecules, demonstrating potential toxicity to living cells. − Numerous studies have indicated that nanomaterials may cause severe structural distortions and the functional loss of biomolecules. − For instance, graphenethe prototype 2D materialand graphene oxides (GOs), possess high cytotoxicity, due to their strongly attractive surface . The strong binding to graphene can cause severe structure distortions of proteins and DNA or destructive extraction of lipids from the cell membrane. ,− , Like coins having two sides, the active surface of nanomaterials finds applications in treatments of environmental pollutants including organic pollutants, pathogenic bacteria, and even antibiotic resistance genes (ARGs) in environmental water resources. ,− For instance, Yu et al reported that GO can remove ARGs more efficiently than the traditional treatment technologies such as chlorination and ultraviolet irradiation. − It was reported that small-sized GO nanosheets can easily insert into the base pairs of plasmid DNA and change the double helix structure of DNA through disturbing the base pair stacking mode . Recent experimental evidences indicated that the ARG removal efficiency might be caused by strong binding of GO with DNA through strong electrostatic attraction .…”

Section: Introductionmentioning

confidence: 99%

Defect-Induced Double-Stranded DNA Unwinding on Graphene

Yang

et al. 2021

J. Phys. Chem. B

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Several works have shown that graphene materials can effectively regulate the double-stranded DNA (dsDNA) structures and are used to remove antibiotic resistance genes in the environment, during which the morphology of the graphene surface plays a key role. However, the mechanism of how different graphene surfaces interact with dsDNA is poorly documented. Here, the interactions of dsDNA with defective graphene (D-Gra) and pristine graphene (P-Gra) have been explored by molecular dynamics simulations. Our data clearly showed that both D-Gra and P-Gra were able to attract dsDNA to form stable bindings. However, the structure evolutions of dsDNA are distinctly different. In detail, D-Gra can initiate quick unwinding of dsDNA and cause significant structural disruption. While for P-Gra, it demonstrated a much weaker capability to disrupt the dsDNA structure. This difference is due to the strong electrostatic interaction between defects and DNA nucleotides. Nucleotides can be highly restricted by the defect while the other parts of dsDNA could move along the transverse directions of D-Gra. This effectively introduces a “pulling force” from the defect that causes the breaking of the hydrogen bonds between dsDNA base pairs. Such force finally leads to the serious unwinding of dsDNA. Our present findings could help us to better understand the molecular mechanism of how the dsDNA canonical B-form was lost upon adsorption to graphene. The findings of the key roles of defects on graphene are beneficial for the design of functional graphenic materials for biological and medical applications through nanostructure engineering.

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Cleavage and transformation inhibition of extracellular antibiotic resistance genes by graphene oxides with different lateral sizes

Cited by 29 publications

References 39 publications

Water lubrication of graphene oxide-based materials

Water lubrication of graphene oxide-based materials

Emerging pollutants—Part II: Treatment

Defect-Induced Double-Stranded DNA Unwinding on Graphene

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