Clinical and radiological features of knee osteoarthritis in patients attending the university hospital of Kinshasa, Democratic Republic of Congo

Abstract

IntroductionThe aim of the present study was to describe the clinical and radiological features of knee osteoarthritis in Congolese outpatients attending the University Hospital of Kinshasa (UHK).MethodsA cross-sectional study was performed in the rheumatology unit of the UHK from January to August 2012. Patients were consecutively recruited. The diagnosis of Osteoarthritis (OA) was based on the criteria of the American College for Rheumatology. Demographic, clinical and x-rays data were collected. The X-rays severity was assessed according to Kellgren and Lawrence's method.Results1049 patients attended the Rheumatology unit of the UHK during the study period. An accurate diagnosis was reported for 839 patients, of whom 376 (44.8%) suffered from OA. Knee OA was diagnosed in 118 patients (31.4% of all OA patients). 101 patients accepted to be included in the study, 78 women (77.2%) and 23 men (22.8%). Their average age was 58.9 ± 10 years. A body mass index (BMI) ≥ 25kg/m2 was observed in 68 patients of whom 28 were obese (BMI ≥ 30kg/m2). The main symptoms were a mechanical pain (100%), swelling (40.6%), crepitus (79.2%) and mobility reduction (X%). Knee deformities were observed in some patients. At baseline, radiological damages > stage 2 of Kellgren-Lawrence were found in 70 patients.ConclusionKnee OA is a common disease among outpatients who attend the unit of Rheumatology of the UHK. Its clinical profile is the same as what is reported in the literature. Obesity and skeletal abnormalities are encountered in the majority of patients.

Assessing the Burden of Osteoarthritis in Africa and the Middle East: A Rapid Evidence Assessment

“…Within this symptomatic/radiographic knee OA population, 94% had grade ≥2 OA and more than 70% had severe, grade 3/4, OA. 25 Asokan et al reported a 33.9% prevalence of symptomatic/radiographic knee OA among a population of female patients ≥40 years of age with mixed etiology OA in Bahrain. 17 …”

“… 25 Asokan et al reported a 33.9% prevalence of symptomatic/radiographic knee OA among a population of female patients ≥40 years of age with mixed etiology OA in Bahrain. 17 …”

“…Categorizing the studies by outcomes, 7 reported on epidemiology 15–17 , 19 , 24 , 25 , 28 (prevalence data only) and 16 reported on humanistic burden. 12–14 , 18–23 , 25–31 No studies reported on economic burden/outcomes, and no studies were identified that reported incidence, survival/death rates, or all-cause mortality rates. All 20 publications were rated as satisfactory or higher quality for risk of bias (Online Resource 2) and all reported knee OA.…”

Oportunidades De Estimulação No Domicílio E Habilidade Funcional De Crianças Com Fatores De Risco Para O Desenvolvimento Motor

“…O aumento do envelhecimento associado a crescente prevalência de obesidade, espera-se que as pessoas que sofram com a osteoartrose de joelho se eleve nos próximos anos. (LUKUSA et al, 2019).…”

LncRNA MIR4435‑2HG inhibits the progression of osteoarthritis through miR‑510‑3p sponging

“…OA leads to the breakdown and gradual loss of joint cartilage, triggering debilitating pain and subsequent disability ( 3 ). The disease mainly affects the aging population, and >37% of individuals aged 60 years or older are affected by OA ( 4 ). At present, arthroscopic surgery and painkiller therapy are the main treatment options for OA; however, these treatment strategies result in 36,000,000 ambulatory care visits and 750,000 hospitalizations annually ( 5 , 6 ), leading to a high socioeconomic burden ( 7 ).…”