Clinical characteristics of oral adenosquamous carcinoma: report of a case and an analysis of the reported Japanese cases

Adenosquamous carcinoma: Histogenetic and molecular insight with a report of a case

“…The clinical presentations of ASC were tumor with ulceration (58%), tumorous mass (26%), and ulcer (16%). [5] Concurrent with this observation, the site of ASC in this case is floor of the mouth and presented as a painless ulcer. Generally, ASC has been considered to be a very aggressive malignancy with a poor prognosis.…”

“…[3,[6][7][8][9][10] However, the Japanese cases examined herein did not reflect such poor prognoses. [5] More such analytical studies should shed light on the behavior and prognosis of ASC.…”

Adenosquamous Carcinoma Affecting the Maxilla: A Case Report and Review

“…This fact led to difficulties in establishing the exact origin of this tumor that included nasal and oral cavities and maxillary sinus [18]. underwent an active treatment [21]. The reasons for the aggressive behavior of ASC are unclear; however it could be explained by an apparent propensity to spread by perineural invasion [17].…”

Adenosquamous carcinoma of unknown primary origin: a case report and literature review

“…The commonest sites of occurrence within the head and neck would appear to be the larynx and oral cavity, according to the previous reviews. 4,6 It is ordinarily difficult to give a histological diagnosis of adenosquamous carcinoma before initial treatment, because the pre-operative diagnosis is generally made from small biopsy specimens that lack either component, particularly the adenocarcinomatous one, which often exists in the deeper portion of the lesion. In the latest literature review of 93 cases, Masand et al reported that 47.4 per cent of cases had regional metastases and 24.7 per cent had distant metastases.…”

“…4,5 Adenosquamous carcinoma is considered to be aggressive and to have a poor clinical outcome. 6 Therefore, it has been suggested that adenosquamous carcinoma may be more common than the published data would suggest 7 and many cases of adenosquamous carcinoma may have been treated inadequately, such as with chemoradiotherapy. 5 There is nearly unanimous agreement about the firstchoice treatment of adenosquamous carcinoma, which is thorough resection with an adequate surgical margin.…”