Clinical Characteristics of Postoperative Skin Scars in Patients With Different Circadian Rhythms Using the Placenta Cryoextract

Аветіков, Давид Соломонович; Toropov, O. A.; Локес, Катерина Петрівна; Voloshyna, Liudmyla; Steblovskiy, D. V.; Boyko, I.V.; Yatsenko, P. I.

doi:10.26724/2079-8334-2021-4-78-7-11

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…Характер рубців оцінювали за сучасною шкалою оцінки рубцевозмінених тканин, розробленою й упровадженою в Полтавському державному медичному університеті. Аналіз проводили за допомогою семи показників на різні терміни спостереження: на 120-у і 240-у добу клінічного дослідження [12].…”

Section: матеріали і методи дослідженняunclassified

Effectiveness of Silicone Materials in Preventing Pathological Scars in Maxillo-Facial Area

2023

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Pathological scars are not only an integral medical and aesthetic problem nowadays, but also serious functional and aesthetic consequences of traumatic and surgical wounds. The purpose of our study is to determine the effectiveness of silicone-based materials in wound healing and the prevention of scar tissue formation. The study was conducted at the Department of Maxillofacial Surgery, the Lviv Regional Clinical Hospital. Twenty patients (10 men and 10 women) with traumatic soft tissue injuries in the maxillofacial area participated in the study were divided into two groups of 10 patients each. The first experimental group received a silicone-based patch after suturing the wound, while the patients of the second clinical (control) group were operated on according to standard techniques without additional methods of scar prevention. The nature of the scars was assessed according to the modern scale for evaluating scarred tissues developed and implemented at the Poltava State Medical University. The analysis was carried out using seven indicators for different periods of the observation (on the 120th and 240th day of the clinical study). On the 240th day of the clinical study, the patients of the first group showed moderate hyperemia in 30% of cases, close to intact skin in 70%, moderate pigmentation in 20%, and isopigmentation in 80%. The scar raised above the skin surface in 20.0% (2 patients) of cases for 1-2 mm, while in the rest, 8 people, the scar raised less than 1 mm. Uniform raising of the scar was observed in 30.0% of cases (3 patients), while the surface was close to intact skin in 70.0% of cases (7 people). 20.0% of cases (2 patients) had a moderately compacted scar, while in 80.0% of cases (8 patients), the scares were assessed as mildly elastic, and only 1 patient complained of mild discomfort (itching). Other participants had no complaints. Non of patients in the first group complained of pain. On the 240th day of the clinical study, the second control group exhibited the following indicators: moderate hyperemia in 70.0% of cases (7 patients) and normal vascularization in 30.0% of cases (3 individuals). Hypopigmentation was observed in 60.0% (6 cases) and isopigmentation in 40.0% of cases (4 patients). The height of the scar above the skin surface was 1-2 mm in 60.0% of cases (6 patients) and less than 1 mm in the remaining 40.0% of cases (4 patients). A uniform increase in scar size was noted in 70.0% of cases (7 cases), while the surface was similar to that of intact skin in 30.0% of cases (3 individuals). Moderately thickened scars were observed in 50.0% of cases (5 patients) and pronounced induration of soft tissues in the other 50.0% of cases (5patients). Regarding subjective sensations, 70.0% (7 patients) had no complaints, 30.0% of cases (3 patients) experienced slight discomfort, and 10.0% (1 patient) reported mild pain, while the remaining 90.0% (9 individuals) had no complaints. Comparing the results of the clinical study on the 240th, the first study group's performance was better and 77.0% lower compared to the second control group. This allows us to suggest that the use of silicone gel after the wound closure, compared to the standard method, promotes the wound healing process and reduces the risk of pathological scarring.

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Section: матеріали і методи дослідженняunclassified

Effectiveness of Silicone Materials in Preventing Pathological Scars in Maxillo-Facial Area

2023

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“…Thus, aesthetic rhinoplasty is considered one of the most frequently requested and performed surgical procedures in this population. However, there is growing agreement that BDD should be considered a contraindication for aesthetic rhinoplasty as there is no favorable outcome [4][5][6][7][8][9][10][11][12]. Therefore, given the ethical, safe and legal considerations associated with aesthetic procedures in these patients, accurate identification and appropriate selection of procedures are crucial.…”

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Individual Psychological Characteristics of Patients With Body Dysmorphic Disorder Seeking Cosmetic Rhinoplasty

Bodnar,

Zhyvotovska,

Skrypnikov

et al. 2023

VPBM

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Connection of the publication with planned research works.The study is a fragment of the research work «Clinical-psychopathological and paraclinical studies and optimization of treatment and rehabilitation measures for the main forms of mental pathology and comorbid disorders», state registration № 0121U108235Introduction.With the increase in the number and popularity of cosmetic procedures and interventions, doctors of related specialties are increasingly faced with patients with body dysmorphic disorder (BDD), characterized by excessive attention to non-existent or minor defects in their appearance [1]. The prevalence of BDD in the general population ranges from 1 to 2%, and in patients with dermatological and cosmetic surgery is from 2.9 to 24% [2-3].BDD includes distorted body perception with excessive concern for an imaginary defect. Most patients experience certain disturbances in social or professional functioning, and as a result of obsessive anxiety they may develop compulsive behavior. In severe cases, there is a risk of suicide. It has been shown that the frequency of suicide in individuals with BDD is 45 times higher than in the general population. This is 2 times more than among people with depression and three A -Work concept and design, B -Data collection and analysis, C -Responsibility for statistical analysis, D -Writing the article, E -Critical review, F -Final approval of the article

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Comparative Characteristics of Clinical Indicators of the Condition of Scar Tissue of the Facial Skin at Different Stages of the Postoperative Period Depending on the Chronotype of the Person

et al. 2022

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The aim: The aim of the study was to improve preventive measures aimed at preventing the formation of pathological scarring of the skin in patients after elective surgery by intra- and postoperative use of cryopreserved placental cells. Materials and methods: The research was conducted in the Department of Maxillofacial Surgery on the basis of the Municipal Enterprise «Poltava Regional Clinical Hospital. M.V. Sklifosovsky» Poltava Regional Council. A total of 60 patients took part in the study, who were hospitalized for planned surgical interventions in the department of maxillofacial surgery Results: We obtained clinical data on the processes of scar formation in patients with morning and evening chronotype on the background of local intraoperative injection of cryopreserved placenta extract into the wound. We have proved that short people with an established evening chronotype need additional preventive measures, especially on the 90th and 180th days of the postoperative period. Conclusions: From our study we can say with confidence that the drug “Cryocel” reduces epithelialization time, promotes optimal wound healing and leads to the formation of more aesthetic scars, which creates optimal both functional and cosmetic results.

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Clinical Characteristics of Postoperative Skin Scars in Patients With Different Circadian Rhythms Using the Placenta Cryoextract

Cited by 3 publications

References 15 publications

Effectiveness of Silicone Materials in Preventing Pathological Scars in Maxillo-Facial Area

Effectiveness of Silicone Materials in Preventing Pathological Scars in Maxillo-Facial Area

Individual Psychological Characteristics of Patients With Body Dysmorphic Disorder Seeking Cosmetic Rhinoplasty

Comparative Characteristics of Clinical Indicators of the Condition of Scar Tissue of the Facial Skin at Different Stages of the Postoperative Period Depending on the Chronotype of the Person

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