Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial

Abstract

Background: Dentinal hypersensitivity is a common problem and there is a growing interest in herbal based formulations for the treatment of oral diseases. This study was conducted to assess the efficacy of a commercially available novel herbal dentifrice in reduction of dentinal hypersensitivity. Methods: A total of 73 subjects (38 males and 35 females; aged 25-60 years) were randomly divided into two groups: Group 1 -a placebo dentifrice (The Himalaya Drug Company Research and Development, Makali, Bangalore) and Group 2 -(test group), a commercially available herbal dentifrice (Hi Ora K, The Himalaya Drug Company Research and Development, Makali, Bangalore). Sensitivity scores for controlled air stimulus and cold water were recorded at baseline, 6 weeks and 12 weeks. Results: The test group was found to be significantly better compared to the placebo group at the end of 6 and 12 weeks in reduction of dentinal hypersensitivity. Conclusions: The novel herbal dentifrice can be recommended for treatment of dentinal hypersensitivity.

Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow‐up analysis

“…In vitro studies have shown that the Spinacia oleracia agent is effective in the occlusion of dentinal tubules through the formation of calcium oxalate crystals. In this review, three studies were included that refer to a statistical improvement in DH with the use of herbal dentifrices, two of which refer to the agent Spinacia oleracea . However, the presence of potassium nitrate in the composition of the described dentifrices does not allow a correct understanding of the true nature of the desensitising effect of Spinacia oleracia in the treatment of DH, since this effect may be due to the nitrate in the composition of the product.…”

Uso de dentífricos y colutorios para el control de la hipersensibilidad dentinaria en adultos: una revisión narrativa.

“…Con respecto a los agentes testeados encontramos (Gráfico 1): arginina, nitrato de potasio, fluoruro de potasio y de amina, citrato de potasio, oxalato de potasio, acetato de estroncio, nano hidroxiapatita, y fosfosilicato de calcio y sodio (CSPS) más conocido como Novamin ® (GlaxoSmithKline Consumer Healthcare, Weybridge, Surrey, Reino Unido). Las sales de potasio fueron las más investigadas, siendo 19 ensayos los que evaluaron alguna de sus formas (14,(16)(17)(18)(19)(20)25,26,28,29,(32)(33)(34)(35)(36)(37)(38)40,41) . De ellas, el agente más testeado fue el nitrato de potasio, 15 estudios evaluaron su eficacia; dos de ellos en colutorios (14,18) , uno en una combinación de colutorio y dentífrico (19) , y 12 en dentífricos al 5% (25,28,29,33,(35)(36)(37)(38)(39)(40)(41) .…”

Comparative efficacy of a herbal and a non‐herbal dentifrice on dentinal hypersensitivity: a randomized, controlled clinical trial

“…In vitro studies have shown that phytocomplexes derived from rhubarb stalks ( Rhubarb rhaponicum ) and spinach leaves ( Spinacia oleracia ) are effective in occluding dentinal tubules through the formation of calcium oxalate crystals, and should be effective for the topical treatment of DH . In our previous preliminary study, a herbal‐based dentifrice containing potassium nitrate and Spinacia oleracia was found to be effective in the treatment of DH, as compared to the placebo group . However no positive control was used in our previous study.…”

“…17 In our previous preliminary study, a herbal-based dentifrice containing potassium nitrate and Spinacia oleracia was found to be effective in the treatment of DH, as compared to the placebo group. 18 However no positive control was used in our previous study.…”