2012
DOI: 10.4236/oju.2012.223030
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Clinical Evaluation of Efficacy and Safety of a Herbal Formulation in Benign Prostatic Hyperplasia: A Single Blind, Randomized, Placebo-Controlled Study

Abstract: Benign prostatic hyperplasia (BPH) is a condition intimately related to ageing. Currently available treatment options for the management of BPH have various limitations and associated adverse effects. A polyherbal formulation is claimed to be beneficial in patients with benign prostatic hyperplasia. This single blind, placebo-controlled study evaluated the clinical efficacy and safety of polyherbal formulation in BPH. Material and Methods: A total of 60 patients who were diagnosed as BPH and who were willing t… Show more

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Cited by 4 publications
(4 citation statements)
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“…For two months, each patient took either a polyherbal formulation or a placebo in a dose of two capsules twice a day with meals. The mean AUA symptom score significantly improved; at the beginning of treatment, the AUA scores for the Polyherbal formulation and placebo groups were 14.60±3.20 and 13.80±4.60, respectively, and at the end of therapy, they were 9.2±2.60 and 12.90±3.80, respectively (p value 0.0001) [23] . 32 patients from Mootraghata who met the criteria for BPH were randomly assigned to one of three treatment groups, and a study on the use of Gokshuradi Vati and Dhanyaka Gokshura Ghrita Matra Basti in the management of BPH was done.…”
Section: Clinical Studies Effect On International Prostate Symptom Sc...mentioning
confidence: 87%
See 1 more Smart Citation
“…For two months, each patient took either a polyherbal formulation or a placebo in a dose of two capsules twice a day with meals. The mean AUA symptom score significantly improved; at the beginning of treatment, the AUA scores for the Polyherbal formulation and placebo groups were 14.60±3.20 and 13.80±4.60, respectively, and at the end of therapy, they were 9.2±2.60 and 12.90±3.80, respectively (p value 0.0001) [23] . 32 patients from Mootraghata who met the criteria for BPH were randomly assigned to one of three treatment groups, and a study on the use of Gokshuradi Vati and Dhanyaka Gokshura Ghrita Matra Basti in the management of BPH was done.…”
Section: Clinical Studies Effect On International Prostate Symptom Sc...mentioning
confidence: 87%
“…Prostate weight (Gms) in the placebo group and Polyherbal formulation was 34.60±8.70 and 32.60±8.30 at the beginning of treatment which becomes 32.60±9.40 and 34.50±6.60, respectively, at the end of treatment. Post-void residual (PVR) volume (ml) in the Polyherbal formulation and placebo group at the beginning of treatment was 85.30±20.20 and 86.20±18.20 and at the end of therapy it was 52.10±23.10 and 89.70±28.30, respectively (p-value 0.0001) [23] . Prostate gland's size had significantly decreased [24] .…”
Section: Effect On Prostate Volume and Post Void Residual Urinementioning
confidence: 95%
“…In a study of Jeyaraman and Patki 24 investigating a polyherbal formulation in BPH patients over a period of 2 months, postvoid residual volume was also measured and a significant reduction was reported from 85.3 to 52.1 mL. The difference was highly significant in comparison to placebo.…”
Section: Discussionmentioning
confidence: 98%
“…10 The Uricare tablet shows moderate activity in the treatment of the Prostate enlargement by showing the reduction in the I-PSS score and improving the quality of Life. Experimental study has assumed that the ingredients of Uricare tablet possesses both α-adreno receptor antagonist and 5α-reductase enzyme inhibitory activities.…”
Section: Discussionmentioning
confidence: 99%