Clinical Evaluation of Methods to Correct Intraocular Pressure Measurements by the Goldmann Applanation Tonometer, Ocular Response Analyzer, and Corvis ST Tonometer for the Effects of Corneal Stiffness Parameters

Bao, Fangjun; Huang, Zixu; Huang, Jinhai; Wang, Junjie; Deng, ManLi; Li, LinNa; Yu, A-Yong; Wang, Qinmei; Elsheikh, Ahmed

doi:10.1097/ijg.0000000000000359

Cited by 32 publications

(34 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Many previous reports used regression analyses to investigate the relationships of IOP measurements using the CST and ORA to measure anatomical and structural parameters such as the CCT [7–9, 11, 12, 18, 19], corneal curvature [9, 11, 18, 19], spherical equivalent [9], and axial length [11, 18]. In the present study, we used stepwise multivariate regression analyses to comprehensively analyze the anatomical and structural factors that affected IOP measurements.…”

Section: Discussionmentioning

confidence: 99%

A Comparison of the Corrected Intraocular Pressure Obtained by the Corvis ST and Reichert 7CR Tonometers in Glaucoma Patients

2017

View full text Add to dashboard Cite

The purpose of the study was to investigate the accuracy of two corrected intraocular pressure (IOP) measurements by Corvis Scheimpflug Technology (CST)-IOPpachy and by corneal-compensated IOP (IOPcc) using the Reichert 7CR (7CR) tonometers. We also investigated the effects of corneal anatomical and structural parameters on the IOP measurements. The participants included 90 primary open-angle glaucoma patients. We assessed the IOP measurements, obtained by the CST, 7CR, and Goldmann applanation tonometer (GAT), using a paired t-test with Bonferroni correction, Bland-Altman plots, and multiple regression analyses. The 7CR-IOPcc gave the highest value (15.5 ± 2.7 mmHg), followed by the 7CR-IOPg (13.7 ± 3.1 mmHg), GAT-IOP (13.6 ± 2.2 mmHg), CST-IOP (10.3 ± 2.6 mmHg), and CST-IOPpachy (9.7 ± 2.5 mmHg). The values of CST-IOPpachy were significantly lower than those obtained by the other IOP measurement methods (all, p < 0.01). The values of 7CR-IOPcc were significantly higher than those obtained by the other IOP measurement methods (all, p < 0.01). Bland-Altman plots showed a mean difference between the GAT-IOP and the other IOP measurements (CST-IOP, CST-IOPpachy, 7CR-IOPg, and 7CR-IOPcc), which were −3.20, −3.82, 0.14, and 2.00 mmHg, respectively. The widths of the 95% limits of agreement between all pairs of IOP measurements were greater than 3 mmHg. With the exception of the 7CR-IOPcc, all of the IOP variations were explained by regression coefficients involving gender, average corneal curvature, and central corneal thickness. The IOP values obtained by the GAT, CST, and 7CR were not interchangeable. Each new IOP measurement device that was corrected for ocular structure had its own limitations.

show abstract

Section: Discussionmentioning

confidence: 99%

A Comparison of the Corrected Intraocular Pressure Obtained by the Corvis ST and Reichert 7CR Tonometers in Glaucoma Patients

2017

View full text Add to dashboard Cite

show abstract

“…Age has recently been proposed as parameter to access the corneal micro-structural properties and hence, to correct the IOP values [31]. Fig 5a shows that age presents a weak correlation even though significant for uncorrected IOP (R 2 = 0.05, p = 0.04).…”

Section: Resultsmentioning

confidence: 96%

“…The influence of the macro-structural parameters has been extensively explored [7,8,31]. In general, CCT has been reported to be more important for tonometry calibration than CR.…”

Section: Discussionmentioning

confidence: 99%

“…[34] obtained an R 2 of 0.183 for 178 eyes whereas Bao et al . [31] obtained an R 2 of 0.221 for 99 eyes. In both those studies, it was observed that IOP measurements are affected by CCT independently of the noncontact tonometer used.…”

Section: Discussionmentioning

confidence: 99%

“…IOP as a function of CR was presented by Bao et al . [31], Kohlhaas et al [8] and Shimmyo et al . [35].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Influence of eye biometrics and corneal micro-structure on noncontact tonometry

Jesus

Majewska

Krzyżanowska-Berkowska

et al. 2017

PLoS ONE

View full text Add to dashboard Cite

PurposeTonometry is widely used as the main screening tool supporting glaucoma diagnosis. Still, its accuracy could be improved if full knowledge about the variation of the corneal biomechanical properties was available. In this study, Optical Coherence Tomography (OCT) speckle statistics are used to infer the organisation of the corneal micro-structure and hence, to analyse its influence on intraocular pressure (IOP) measurements.MethodsFifty-six subjects were recruited for this prospective study. Macro and micro-structural corneal parameters as well as subject age were considered. Macro-structural analysis included the parameters that are associated with the ocular anatomy, such as central corneal thickness (CCT), corneal radius, axial length, anterior chamber depth and white-to-white corneal diameter. Micro-structural parameters which included OCT speckle statistics were related to the internal organisation of the corneal tissue and its physiological changes during lifetime. The corneal speckle obtained from OCT was modelled with the Generalised Gamma (GG) distribution that is characterised with a scale parameter and two shape parameters.ResultsIn macro-structure analysis, only CCT showed a statistically significant correlation with IOP (R2 = 0.25, p<0.001). The scale parameter and the ratio of the shape parameters of GG distribution showed statistically significant correlation with IOP (R2 = 0.19, p<0.001 and R2 = 0.17, p<0.001, respectively). For the studied group, a weak, although significant correlation was found between age and IOP (R2 = 0.053, p = 0.04). Forward stepwise regression showed that CCT and the scale parameter of the Generalised Gamma distribution can be combined in a regression model (R2 = 0.39, p<0.001) to study the role of the corneal structure on IOP.ConclusionsWe show, for the first time, that corneal micro-structure influences the IOP measurements obtained from noncontact tonometry. OCT speckle statistics can be employed to learn about the corneal micro-structure and hence, to further calibrate the IOP measurements.

show abstract

Corneal Biomechanics and Integrated Parameters for Keratoconus Diagnosis

Salomão

Lima

Mello³

et al. 2021

New Frontiers for the Treatment of Keratoconus

View full text Add to dashboard Cite

Clinical Evaluation of Methods to Correct Intraocular Pressure Measurements by the Goldmann Applanation Tonometer, Ocular Response Analyzer, and Corvis ST Tonometer for the Effects of Corneal Stiffness Parameters

Abstract: CCT accounted for the majority of variance in IOP, whereas age and R had a much smaller effect. The IOP correction processes studied were successful in reducing reliance of IOP measurements, especially those by GAT and CVS, on CCT in a healthy Chinese population.

Cited by 32 publications

References 50 publications

A Comparison of the Corrected Intraocular Pressure Obtained by the Corvis ST and Reichert 7CR Tonometers in Glaucoma Patients

A Comparison of the Corrected Intraocular Pressure Obtained by the Corvis ST and Reichert 7CR Tonometers in Glaucoma Patients

Influence of eye biometrics and corneal micro-structure on noncontact tonometry

Corneal Biomechanics and Integrated Parameters for Keratoconus Diagnosis

Contact Info

Product

Resources

About