Clinical Experience with Suction Biopsy of the Rectal Mucosa

Flick, Arnold L.; Voegtlin, Karl F.; Rubin, Cyrus E.

doi:10.1016/s0016-5085(62)80121-8

Cited by 51 publications

(8 citation statements)

References 20 publications

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“…Dick and Grayson (1961) found an abnormalhistology in nine out of 19 symptom-free patients in whom sigmoidoscopy was normal. On the other hand, Flick, Voegtlin, and Rubin (1962) stated that they found no frankly abnormal biopsy in any patient with a normal mucosa on sigmoidoscopy. They imply a greater accuracy of sigmoidoscopic interpretation and mention that they use 'early criteria'.…”

Section: Discussionmentioning

confidence: 99%

Persistence of mucosal abnormality in ulcerative colitis.

Dick¹,

Holt²,

Dalton³

1966

Gut

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Section: Discussionmentioning

confidence: 99%

Persistence of mucosal abnormality in ulcerative colitis.

Dick¹,

Holt²,

Dalton³

1966

Gut

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“…Because of the difficulty of distinguishing histological changes in mild or quiescent colitis from the range of appearances seen in normal subjects (Flick, Voegtlin, and Rubin, 1962) care was taken, in the manner described above, to eliminate observer bias and to ensure that the results were reproducible. If these measures had not been taken it would not have been possible to make a confident diagnosis of colitis in two cases where the only abnormality was the presence of plasma cells in the lamina propria in excess of normal numbers (Fig.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory bowel disease in ankylosing spondylitis

Jayson¹,

Salmon²,

Harrison³

1970

Gut

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SUMMARY Routine detailed gastroenterological investigations were performed in a series of 47 ankylosing spondylitics. Evidence of chronic inflammatory bowel disease was found in eight patients, a prevalence of 17 %. Unsuspected bowel disease was found in the absence of symptoms in three of these patients.The association between ulcerative colitis and ankylosing spondylitis has been well documented.

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“…The relationship between the sigmoidoscopic and microscopic appearances of the rectal mucous membrane in colitis has been studied by Truelove and Richards (1956), Dick and Grayson (1961), Matts (1961), and Flick, Voegtlin, and Rubin (1962). Each of these groups of workers has shown that microscopic inflammatory changes in rectal mucosa may be present when sigmoidoscopic appearances are normal, although in general a close correlation was observed between macroscopic and microscopic appearances.…”

mentioning

confidence: 99%