2009
DOI: 10.1159/000213070
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Clinical Manifestations and Diagnosis of Lyme Borreliosis

Abstract: Lyme borrelosis is a multi-systemic disease caused byBorrelia burgdorferisensu lato. A complete presentation of the disease is an extremely unusual oberservation, in which a skin lesion follows a tick bite, the lesion itself is followed by heart and nervous system involvement, and later on by arthritis; late involvement of the eye, nervous system, joints and skin may also occur. Information on the relative frequency of individual clinical manifestations of Lyme borreliosis is limited; however, the skin is most… Show more

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Cited by 165 publications
(169 citation statements)
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References 234 publications
(533 reference statements)
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“…However, without antibiotic therapy, spirochetes may survive for several more years, and may cause latestage complications. The prevalence of specific infectious complications reflects the distribution of genospecies in the region, with Borrelia burgdorferi more commonly associated with arthritis, B garinii with neurologic disease and B afzelii with skin manifestations (15).…”
Section: Epidemiologymentioning
confidence: 99%
“…However, without antibiotic therapy, spirochetes may survive for several more years, and may cause latestage complications. The prevalence of specific infectious complications reflects the distribution of genospecies in the region, with Borrelia burgdorferi more commonly associated with arthritis, B garinii with neurologic disease and B afzelii with skin manifestations (15).…”
Section: Epidemiologymentioning
confidence: 99%
“…The patient group consisted of 50 women and 5 men, all of whom met the American College of Rheumatology classification criteria for SSc (2). The median age was 50 years (range 18-78), and the median disease duration was 9 years (range 1-39).…”
mentioning
confidence: 99%
“…Sezonska distribucija ekstrakutanih manifestacija je manje izražena usled varijabilnog vremenskog perioda od infekcije do pojave oboljenja, koji je obično duži nego za erythema migrans (16). Kliničke manifestacije su iste kod dece i kod odraslih, osim meningopoliradikuloneuritisa i acrodermatitis chronica atrophicans koji se ne javljaju kod dece (kod dece se češće javlja multipli erythema migrans); učestalost različitih kliničkih manifestacija je više varijabilna kod dece različitih starosnih grupa nego kod odraslih (17)(18)(19).…”
Section: Epidemiologijaunclassified
“…U Severnoj Americi sve manifestacije lajmske borelioze, uključujući i lajmsku neuroboreliozu prouzrokuje B. burgdorferi sensu stricto, dok u Evropi lajmsku neuroboreliozu najčešće prouzrokuje B. garinii, ređe B. afzelii, i retko B. burgdorferi sensu stricto (17,18,33,37).…”
Section: Lajmska Neuroboreliozaunclassified