Clinical outcomes with transfer of blastocyst or cleavage stage embryos: high order pregnancies, newborn weights and sex ratios.

Rodriguez, H.F.; Bustillo, María; Lapalme, J; Riley, Elizabeth; Eisermann, Juergen; Thompson, Katherine

doi:10.1016/s0015-0282(01)02502-x

Cited by 4 publications

(5 citation statements)

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“…When we analyzed the M/F ratio after adding data from four unpublished studies (20)(21)(22)(23), blastocyst transfer resulted in an M/F ratio of 1.36 (1,071/ 790), which was significantly different from 1.05 (1,279/1,220) for the early cleavage-stage ET. The OR using fixed effect model was 1.29 (95% CI 1.13-1.47; I 2 ¼ 0%), which is almost equal to the OR including four published studies.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Impact of blastocyst transfer on offspring sex ratio and the monozygotic twinning rate: a systematic review and meta-analysis

Chang

Lee

Jee

et al. 2009

Fertility and Sterility

166

102

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Section: Resultsmentioning

confidence: 99%

“…Five abstracts were excluded because of the absence of peer-review process and a full-length original article (15,(20)(21)(22)(23). Two reports on sex ratio imbalance after blastocyst transfer were excluded because there were no comparative data for blastocyst versus cleavage-stage ETs (5,24).…”

Section: Studies Identifiedmentioning

confidence: 99%

Impact of blastocyst transfer on offspring sex ratio and the monozygotic twinning rate: a systematic review and meta-analysis

Chang

Lee

Jee

et al. 2009

Fertility and Sterility

166

102

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“…They either find more males born after fresh blastocyst transfer compared to spontaneous conception [19] or compared to day 3 transfer [8,17,21], or they show no differences neither in sex ratio nor in growth rate of embryos [9,23,[26][27][28][30][31][32].…”

Section: Discussionmentioning

confidence: 99%

“…Some earlier studies in human ART (assisted reproduction technology) have shown that blastocyst transfer may favour male offspring [17-21, 24, 29] while others did not come to the same conclusion [3,16,26,27,30]. However, reporting criteria are unclear as to selection between IVF and ICSI.…”

Section: Introductionmentioning

confidence: 99%

Blastocyst transfer and gender: IVF versus ICSI

Hentemann

Briskemyr

Bertheussen

2009

J Assist Reprod Genet

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Purpose To investigate the difference in sex ratio in our centre after day 5 embryo transfer among neonates delivered after fresh in vitro fertilization (IVF), fresh intra cytoplasmatic sperminjection (ICSI) and frozen embryo replacement (FER) compared to expected sex ratio in normal population. Methods Retrospective data after IVF/ICSI/FER therapy from 1995 -2007 and data from the literature on similar subjects. Results Among a total of 420 births after day 5 transfer, there were 225 male and 195 female babies. However, after ICSI alone 30 were female and 21 male. Adding all available data from the literature on gender ratio after long term culture, the ratio of male births to total births (0.545) was significantly (p=0.004) different from the expected ratio (0.515) Conclusions It appears that significantly more males are born than expected after day 5 transfer in IVF. However, a subgroup analysis in our data comparing IVF, ICSI and FER revealed more females born after ICSI and FER, suggesting that further research is needed in this area.

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“…However, the data from their study was available in the proceedings of a national meeting (10). In addition, four abstracts that addressed this issue were found (11)(12)(13)(14). Overall, only one of the six studies (14) showed a significant difference in the M/F ratio in BT (81/44) compared to day 3-ET (326/321), while the others demonstrated trends which did not achieve statistical significance (Table I).…”

Section: Resultsmentioning

confidence: 99%