Clinical presentation and outcome of sinonasal tumors in a Nigerian Tertiary Hospital – 6-year review

Alabi, BS; Afolabi, OA; Omokanye, H.K.; Dunmade, AD; Ayodele, Samuel O.

doi:10.4103/nmj.nmj_265_14

Cited by 9 publications

(12 citation statements)

References 13 publications

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“…In this study the commonest disease conditions found were rhinosinusitis followed by sinonasal and nasopharyngeal tumors similar to other findings [6,7]. The commonly seen clinical features of sinonasal diseases in the present study were nasal blockage, rhinorrhea and epistaxis as was also documented by other works [13]. In addition those with advanced disease extending to congruent structures such as the eye/orbit had features such proptosis and facial asymmetry [14,18,19] Majority of the tumours/ masses were seen in advanced stages as already documented by others and some of the factors deduced for this included; self-medication, quackery, poverty and fact that the sinonasal region is an area that appears hidden [13,16,17].…”

Section: Discussionsupporting

confidence: 91%

“…it is rare in children [11] and seen more in ages >20years [12]. Some of these diseases are known to have high burden of morbidity and mortality with clinical presentations depending on the site and extension of the disease [13]. The commonly documented features include nasal obstruction, discharge, facial swelling, epistaxis, nasal mass, headaches [14,15,13].…”

Section: Introductionmentioning

confidence: 99%

“…Some of these diseases are known to have high burden of morbidity and mortality with clinical presentations depending on the site and extension of the disease [13]. The commonly documented features include nasal obstruction, discharge, facial swelling, epistaxis, nasal mass, headaches [14,15,13]. it is also known that these patients tend to present very late to the hospital and hence are seen as very advanced disease [16,17].…”

Section: Introductionmentioning

confidence: 99%

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Clinicopathologic profile of sinonasal diseases in a tertiary hospital in Port Harcourt

Ibekwe¹,

Oghenekaro²

2021

World J. Adv. Res. Rev.

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Background: In a typical ear nose and throat clinic, disease conditions involving the nose and paranasal sinuses are not uncommon. The aim of this study is to determine the clinicopathologic profile of these diseases as it occurs in university of Port Harcourt teaching hospital. Methodology: A retrospective descriptive analysis of all patients with diagnosis of sinonasal disease that presented in the ear nose and throat surgery department of university of Port Harcourt teaching hospital within the period of 5years (from 2016 – 2020). Data retrieved were biodata, clinical features, diagnosis and treatment, these were all collated and analysed. Patients without complete records were excluded. The patients recruited had clinical diagnosis which was aided by radiological investigations and confirmed by histology. Result: A total of 68 patients were studied within the 5year period. There were 35males and 33 females. The mean age was 33.96+/_17.9 years. The age groups 11-20 and 41-50 were more affected. Rhinosinusitis was the commonest condition seen while inflammatory polyp was the commonest histologic diagnosis. Polypectomy with bilateral antrostomy was the commonly done surgery in 26.4% age. Conclusion: Disease of the nose and paranasal sinuses are commonly seen in ENT practice and rhinosinusitis is the commonest entity encountered with inflammatory polyp as the commonest histopathologic finding. Squamous cell carcinoma was the commonest malignant lesion seen occurring more in males. Age distribution of the diseases was statistically significant.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinicopathologic profile of sinonasal diseases in a tertiary hospital in Port Harcourt

Ibekwe¹,

Oghenekaro²

2021

World J. Adv. Res. Rev.

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“…We studied different occupational exposures among the study population and we surprisingly found domestic workers were the most vulnerable groups among all (20%) followed by agricultural workers and manual labour (12.5% each). This finding is very similar with the findings by B. S. Alabi et al 9 They conducted a research on sinonasal malignancy in the Nigerian tertiary hospital over 6 years where they similarly found largest group (29%) was exposed to indoor cooking and wood dust most likely in the form of firewood for cooking. In addition, cigarette smoking (18%) was found to be an important risk factor in their study which is similar to our results.…”

Section: Discussionsupporting

confidence: 90%

Sinonasal Tumour- A Clinico-Pathological Study in a Tertiary Care Hospital

Jana¹,

Mandal²

2019

IJCMR

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Introduction: Sinonasal tumours are relatively uncommon tumours in the head-neck region. The aim of the present study was to study the clinico-pathological profile of the sinonasal tumours and its management. Material and methods: It was a Prospective, observational study. Forty Patients with sinonasal tumours, attending the otorhinolaryngology and Head-Neck surgery department of a tertiary-care hospital, Kolkata from October 2017 to September 2018 were selected for the study. Previously treated cases of sinonasal tumour with recurrence were excluded. They were evaluated by detailed history taking, proper clinical examination, relevant radiological imaging followed by biopsy. A clinico-pathological profile was made from the data obtained from these patients. Patients were treated either by surgery, radiotherapy or chemotherapy or a combination as appropriate and followed up regularly. Results: There were 27 males and 13 females in the present study with a male: female ratio of 2:1. Commonest age group was 11 to 20 years. Maximum number of patients encountered were students (30%) followed by domestic workers (20%). Nasal obstruction and epistaxis were the most common mode of presentation (65% each). Out of 40 cases, 25 (62%) had benign and 15(38%) had malignant tumour. Juvenile angiofibroma and maxillary carcinoma were the most common under the benign and malignant varieties of sinonasal tumours respectively. Conclusion: Timely diagnosis and early treatment will decrease the burden of morbidity and mortality in these patients. This study recommends awareness regarding the disease process and health education to people regarding maintenance of hygienic conditions and utilization of health facilities.

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“…Chemotherapy is of only palliative value as suggested by several series. 9 These factors must be taken into account while planning treatment of a case of ACC.…”

Section: Discussionmentioning

confidence: 99%

A dormant yet belligerent tumour, the sinonasal adenoid cystic carcinoma- A case report

Vasudevan¹,

Apoorva

Sanikop³

2022

IJPO

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Adenoid cystic carcinoma, also known as cribriform tumour or Cylindroma owing to the cellular arrangement or type of tissue that it originates from, is rare and shows perineural invasiveness as a pathognomic feature making treatment challenging. The tumour is known to arise in the salivary glands and seldom seen in the nasal cavity or paranasal sinuses. We here present a rare case of ACC occurring beyond its usual premise.A male patient aged 32 presented with unilateral nasal obstruction and epistaxis and on examination a growth in the right nasal cavity was noted to peculiarly arise from beneath the mucosa of the nasal floor, extending posteriorly up to the choana, not involving the turbinates or septum. DNE with biopsy was done and CECT PNS was done for further evaluation and the mass was diagnosed to be stage III sinonasal adenoid cystic carcinoma.This tumour originates from minor salivary glands and its presentation in the nose and paranasal sinuses has been reported to be very sparse. This is perhaps a reason for it to be missed out in daily practice due to clinical features being similar to several inflammatory and neoplastic diseases of the nose and paranasal sinuses. Histopathological cribriform and tubular subtypes are less aggressive than solid form and that determine the prognosis. It is a disease of 6th and 7th decade, slow growing and locally invasive very unusual to find it in a young patient such as ours.Though uncommon the ACC mustn’t go undiagnosed and must be differentiated from commoner nasal masses. Otorhinolaryngologists need to work in collaboration with pathologists and oncologists to accurately diagnose and treat this belligerent tumour in a multifaceted approach. Complete surgical excision with post-operative radiotherapy is the most accepted treatment plan

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Clinical presentation and outcome of sinonasal tumors in a Nigerian Tertiary Hospital – 6-year review

Cited by 9 publications

References 13 publications

Clinicopathologic profile of sinonasal diseases in a tertiary hospital in Port Harcourt

Clinicopathologic profile of sinonasal diseases in a tertiary hospital in Port Harcourt

Sinonasal Tumour- A Clinico-Pathological Study in a Tertiary Care Hospital

A dormant yet belligerent tumour, the sinonasal adenoid cystic carcinoma- A case report

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