Clinical Profile of Patients Presenting With Anemia in a Tertiary Care Rural Hospital of Western Maharashtra

Chandurkar, Milind; Pendalya, Shrivastava

doi:10.5455/ijcbr.2017.34.17

Cited by 3 publications

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“…Milind et al also found nutritional cause leading to iron deficiency anaemia in 50% cases followed by chronic systemic diseases in 30% cases, then inflammatory bowel disease in 10% cases. 12 Hence, the findings in my study are in consistency with Milind's study. In the present study, maximum patients had severe anaemia with 46 cases (i.e.…”

Section: Discussionsupporting

confidence: 90%

“…In our study, the most common presenting symptoms in patients with iron deficiency anaemia were generalised weakness with easy fatigueability followed by breathlessness, pedal edema and palpitations. Milind et al [12] had the most common presenting symptom of easy fatigueability in 80% almost same as in my study followed by breathlessness in 76%, palpitations in 64%, swelling of feet in 40% and chest pain. Ali Shah et al had tiredness in 42% cases, followed by breathlessness in 30%.…”

Section: Discussionsupporting

confidence: 77%

“…Milind et al found pallor in 94% cases, almost same as in our study followed by pedal oedema in 40%, koilonychias in 20%, icterus in 18%. 12 Rinku et al had most common physical finding of pallor in 90% cases followed by pedal oedema and koilonychias and icterus. 13 Hence, the results in the above studies and in our study are in consistency.…”

Section: Discussionmentioning

confidence: 95%

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A cross-sectional observational study assessing the clinical profile of patients with iron deficiency anaemia

2020

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Background: Our objective in this research was to study the clinical profile of patients having iron deficiency anaemia.Methods: This was an observational cross sectional study conducted in Medicine out-patient and in-patient departments of Baroda Medical College and SSG Hospital, Vadodara from February, 2018 to November, 2018 and included all patients (N=50) above eighteen years of age who were diagnosed on admission with microcytic hypochromic or normocytic normochromic anaemia. Following detailed history, general examination and basic haematological investigations like complete blood count, haemoglobin, mean corpuscular volume, etc., statistical analysis of the data was performed.Results: In the present study, it was found that maximum number of patients belonged to a younger age group (mean=36.82 years) with a majority being females (74%). Most common presenting complaint was weakness seen in 96% cases while the commonest clinical finding was pallor present in 100% cases followed by koilonychia in 32%. The most common cause of iron deficiency anaemia was nutritional seen in 60% patients.Conclusions: Generalised weakness, breathlessness, and pedal edema were the commonest presenting complaints in our study while pallor, koilonychia, and pedal edema were the most common clinical findings. Maximum number of patients had IDA due to a nutritional cause. Chronic gastrointestinal bleeding, inflammatory bowel disease, and menorrhagia are other causes of IDA. Amongst addicted, alcohol addiction seen in most cases.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 77%

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A cross-sectional observational study assessing the clinical profile of patients with iron deficiency anaemia

2020

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Utility of Peripheral Blood Smear Examination in the Presence of Automated Haematology Analyser with Reference to Anaemia

Hafiz¹,

Salaria²,

Koul³

2019

jemds

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BACKGROUND Anaemia is a global public health problem affecting both developing and developed countries. The morphological typing of anaemia is essential in clinical haematology for diagnostic and treatment purposes. Over the past few years, complete blood count (CBC) by automated haematology analysers and microscopic examination of peripheral smear have complemented each other to provide a comprehensive report on patient's blood sample. Despite this wealth of information, there are still morphological abnormalities that are critical in the differential diagnosis of anaemia and that can be determined only from a blood smear. The present study aims to evaluate the utility of peripheral blood smear examination in presence of automated haematology analyser with reference to anaemia after correlating type of anaemia based on RBC indices obtained from automated haematology analyser and on peripheral blood smear examination. METHODS This is a cross-sectional study conducted for a period of one year from November 1, 2017 to October 31, 2018 on 100 anaemic patients of Government Medical College, Jammu and Associated Hospitals. EDTA anticoagulated samples were received in the laboratory and run on automated haematology analyser to obtain complete blood count including RBC indices. Simultaneously, well prepared and tongue shaped peripheral blood smears stained by Leishman's stain were studied in detail to observe the morphology of red blood cells. RESULTS On classifying anaemias into five major groups, it was seen that there were 40 patients of normocytic normochromic anaemia with normal RDW which correlated well with 40 patients of normocytic normochromic anaemia on peripheral blood film examination. Normocytic hypochromic anaemia with normal RDW was seen in 5 patients, whereas PBF showed normocytic hypochromic anaemia in 7 patients. 31 patients had microcytic hypochromic anaemia (with normal and raised RDW) as per analyser generated indices which correlated well with 29 patients of microcytic hypochromic anaemia on PBF. Both analyser and PBF showed that 10% patients had macrocytic anaemia. Dimorphic anaemia was seen in 14% patients on PBF. Out of 100 cases, 84% (84) of the cases showed concordance in the type of anaemia by analyser generated RBC indices and on peripheral blood film examination. Only 16% cases showed discordance in the type of anaemia which needed peripheral blood film examination for correct morphological classification of anaemia. CONCLUSIONS RBC parameters on analyser along with PBF findings are complimentary to each other rather than being the substitute. PBF is very important in certain clinical settings in patients with normocytic normochromic anaemia with raised RDW, pancytopenia and patients of fever who show normal or slightly abnormal parameters on analyser. Each haematology report has to be interpreted along with clinical presentation of the patient in order to arrive at diagnosis.

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Morphological types of anaemia integrated with distribution of red cell and platelet indices: Study in a rural tertiary healthcare centre

Shetty¹,

Saha²,

Komala³

2021

IJPO

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Anaemia is a critical global health problemA good morphological subtyping of anaemia can guide clinician in further patient management. With the advent of automation, red cell and platelet indices are available from the routinely used blood cell counters in the laboratory, these supplemented with peripheral smear examination help in a good categorization of anaemia. Aim of this study is to study the morphological types of anaemias in the adults with the Objectives of Categorization of the anaemias based on morphology and to study the distribution of the red cell and platelet indices in the same.: It was a prospective study conducted in the hematology wing of our central diagnostics over a period of three months and a total of 520 cases, which were morphologically classified according to the analyzer indices and peripheral smear. Distribution of the red cell and platelet indices in the different categories of anaemia were also noted. A majority of the anaemias were microcytic hypochromic in type (67.1%) followed by normocytic normochromic anaemias (26.5%). Increased RDW was seen in microcytic hypochromic anaemias (55%) and normocytic normochromic anaemias (6.9%). The Mean platelet count/ mean platelet volume was increased in microcytic anaemias compared to others. : Anaemias in the rural set up are predominantly of the microcytic in type. A good knowledge of the variation in RBC indices, RDW and platelet /mean platelet volume ratio along with a peripheral smear can help the reporting haematologist identify early stages of iron deficiency anaemia and can give a precise and accurate anaemia categorization at the basic entry level of laboratory investigation. Interpretation of variation in RBC and platelet indices though often neglected can contribute significantly to categorize the anaemia.

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Clinical Profile of Patients Presenting With Anemia in a Tertiary Care Rural Hospital of Western Maharashtra

Cited by 3 publications

References 0 publications

A cross-sectional observational study assessing the clinical profile of patients with iron deficiency anaemia

A cross-sectional observational study assessing the clinical profile of patients with iron deficiency anaemia

Utility of Peripheral Blood Smear Examination in the Presence of Automated Haematology Analyser with Reference to Anaemia

Morphological types of anaemia integrated with distribution of red cell and platelet indices: Study in a rural tertiary healthcare centre

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