Clinical Profiles of Hypertrophic Cardiomyopathy With Apical Phenotype  Comparison of Pure-Apical Form and Distal-Dominant Form

Kubo, Toru; Kitaoka, Hiroaki; Okawa, Makoto; Hirota, Takayoshi; Hoshikawa, Eri; Hayato, Kayo; Yamasaki, Naohito; Matsumura, Yuichi; Yabe, Toshikazu; Nishinaga, Masanori; Takata, Jun; Doi, Yasufumi

doi:10.1253/circj.cj-09-0438

Cited by 48 publications

(30 citation statements)

References 36 publications

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“…6 One study cited that 25% of Japanese individuals with HCM have an apical variant. 6 One study cited that 25% of Japanese individuals with HCM have an apical variant.…”

Section: Discussionmentioning

confidence: 99%

“…4 However, in non-Asian populations the reported prevalence is 1%-3%. 6 It is well known that there is overlap between AHCM, mid-cavitary hypertrophic cardiomyopathy, and apical aneurysmal formation. Although AHCM has a more benign course compared to HCM, there is a higher risk of arrhythmia and thromboembolic phenomena after development of an apical aneurysm.…”

Section: Discussionmentioning

confidence: 99%

“…However, a rarer variant is apical wall hypertrophy which is more commonly found in Asian populations. 6 One study cited that 25% of Japanese individuals with HCM have an apical variant. 4 However, in non-Asian populations the reported prevalence is 1%-3%.…”

Section: A S E Rep Ortmentioning

confidence: 99%

“…Although AHCM has a more benign course compared to HCM, there is a higher risk of arrhythmia and thromboembolic phenomena after development of an apical aneurysm. 6 It is well known that there is overlap between AHCM, mid-cavitary hypertrophic cardiomyopathy, and apical aneurysmal formation. 3 There are also case reports of AHCM progressing to develop mid-ventricular cavitary hypertrophy with apical aneurysms.…”

Section: A S E Rep Ortmentioning

confidence: 99%

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The evolution of apical hypertrophic cardiomyopathy: Development of mid‐ventricular obstruction and apical aneurysm 11 years after initial diagnosis

Singam

Stoddard

2019

Echocardiography

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“…6 One study cited that 25% of Japanese individuals with HCM have an apical variant. 6 One study cited that 25% of Japanese individuals with HCM have an apical variant.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: A S E Rep Ortmentioning

confidence: 99%

Section: A S E Rep Ortmentioning

confidence: 99%

See 2 more Smart Citations

The evolution of apical hypertrophic cardiomyopathy: Development of mid‐ventricular obstruction and apical aneurysm 11 years after initial diagnosis

Singam

Stoddard

2019

Echocardiography

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“…But it was Yamaguchi that described the syndrome and its ventriculographic features in 1979 [3]. Kubo and col-leagues [4] used echocardiography in a cohort of 264 patients to define the imaging characteristics and Chen et al [5] utilized 2D echocardiography to further classify apical HCM and to assess the wall thickness. Kitaoka et al found the apical HCM in 15% of Japanese and 3% of American patients of HCM.…”

Section: Review Of Literaturementioning

confidence: 99%

Apical Left Ventricular Hypertrophic Cardiomyopathy: A Case Report

Muthiah¹

2016

CRCM

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Apical hypertrophic cardiomyopathy (apical HCM) is a rare variant of hypertrophic cardiomyopathy with a prevalence of 1%-2% in Asian population and carries a benign prognosis. It is usually silent in early stages and manifests in adults with a suspicion of typical ECG changes of giant T wave inversion in left precordial leads. Transthoracic echocardiography is the mainstay of non-invasive diagnosis and provides a heterogeneous appearance of its morphological features with a spade-shaped LV (left ventricular) cavity. Background of this case study describes the apical HCM in an asymptomatic male at the age of 54 years old and also predicts the mixed and mid-ventricular forms of left ventricular HCM at this region of Thoothukudi in India.

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Syncope in a Middle-aged Man

2021

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A man in his 40s with hypertension was brought to the emergency department after becoming unresponsive during descent on a commercial flight. He was alert and oriented with normal heart rate and blood pressure by emergency medical services evaluation and in the emergency department. He had no recollection of the event, with history notable only for more than usual alcohol use the 2 days prior, including drinking just prior to boarding the plane. A 12-lead electrocardiogram (ECG) was obtained (Figure).Question: Based on the ECG findings, what is the most likely diagnosis? InterpretationThe ECG showed normal sinus rhythm with left ventricular hypertrophy (LVH) by the Sokolov-Lyon criteria and likely intra-atrial conduction delay with a biphasic P wave in leads III and aVF. There were 1-to 2-mm ST-segment elevations in leads V 1 to V 3 with 2-to 3-mm ST depressions in leads V 5 to V 6 . There were T-wave inversions (TWIs) in leads I, aVL, II, and aVF and deep inversions in leads V 4 to V 6 .

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Clinical Profiles of Hypertrophic Cardiomyopathy With Apical Phenotype Comparison of Pure-Apical Form and Distal-Dominant Form

Cited by 48 publications

References 36 publications

The evolution of apical hypertrophic cardiomyopathy: Development of mid‐ventricular obstruction and apical aneurysm 11 years after initial diagnosis

The evolution of apical hypertrophic cardiomyopathy: Development of mid‐ventricular obstruction and apical aneurysm 11 years after initial diagnosis

Apical Left Ventricular Hypertrophic Cardiomyopathy: A Case Report

Syncope in a Middle-aged Man

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