Clinical research of effects of retaining the uterine blood supply hysterectomy on ovarian function

Abstract

Abstract. Objective To evaluate the effect of hysterectomy for reserving the uterine blood supply on ovarian endocrine function and on symptoms of menopausal transition. Methods Uterine benign lesions should be line the uterus times total resection in 100 patients were randomly divided into hysterectomy group of retaining uterus vascular supply group(research group,n=50) and traditional total hysterectomy group (the control group, n=50), comparing two groups in operation time, intraoperative bleeding ,postoperative fever and residual polyp, blood tests were taken to check the serum sex hormone levels change and clinical observation for perimenopausal symptoms before and postoperative three months, six months, one year and two years at the same time respectively. Results There was no significant difference between two groups in operation time, intraoperative blood loss, postoperative fever and residual polyp (P>0.05). There was no significant difference among research group before and after operation in serum sex hormones(P>0.05),the symptoms of the menopausal transition hardly appear; postoperative FSH, LH increased significantly in control group (P<0.05),E2 decrease (P<0.05), perimenopausal symptoms appeared more often. Conclusion The effect of uterus hysterectomy for retaining vascular supply on ovarian endocrine function is less than the traditional total hysterectomy, this operation has a certain importance to preserve ovarian function and delay the occurrence of premature ovarian aging.

Study on serum phosphate level in surgical and natural menopausal women

“…During hysterectomy, the bilateral uterine artery is cut off. Thus, the anastomosis between ovarian and uterine artery is disrupted leading to decrease in ovarian stromal blood flow result in ovarian follicular degeneration and subsequent decrease in ovarian hormone production [21].…”