Clinical study on increased serum thyroxine-binding globulin in cancerous state.

Measurement of serum thyroxine binding prealbumin in various thyroidal states by radioimmunoassay.

“…The fall in the serum TBPA concentration following acute stress has been shown to be due to the reduction in the hepatic synthesis of this protein rather than the increase in catabolism or urinary excretion (Socolow et al, 1965;Oppenheimer et al, 1965). We also reported patients with cancer with high serum TBG levels, and these patients in contrast showed low TBPA levels with slightly higher FT4 levels (Kajita et al, 1981). However, Woeber and Ingbar (1968) reported that the Endocrinol.…”