Clinical Study Remineralization Effect of Mineralization Varnish

Damyanova, Dobrinka; Angelova, Sirma; Targova-Dimitrova, Teodora

doi:10.9790/0853-150804134136

Cited by 3 publications

(2 citation statements)

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“…According to many researchers [27,33,35,[39][40][41][42][43], the CaF 2 formation process, in addition to a sufficiently high concentration of fluoride ions, is also affected by calcium and phosphate ions present in the oral environment, and the quantity of which is insufficient to bind the whole released fluoride [33,[44][45][46][47]. The supply of these ions in second-generation varnishes, according to Attin et al [41], causes deposits of more calcium fluoride on the enamel surface, which in turn enhances the therapeutic effect [32,44,45,[48][49][50][51][52][53][54][55][56][57][58][59]. According to Ogaard [35], these deposits can be observed in vitro at a high magnification up to 4 months after application.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Comparison of the Fluoride Ion Release from the First- and Second-Generation Fluoride Varnishes

2023

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Fluoride varnishes, both the first and the second generations, are effective in inhibiting caries, especially in children and adolescents, by reducing it on average by 43% for permanent teeth and 37% for deciduous teeth. The aim of this study was to evaluate the dynamics of in vitro fluoride ion release from first- (Duraphat) and second-generation (MI Varnish and Embrace Varnish) fluoride varnishes and the impact of the type of varnish, the time from its application and the pH of the environment on this process. Materials and methods: The test material (90 specimens), prepared from extracted human teeth, were divided into nine groups of 10 specimens each. Measured amounts of the examined varnishes were applied onto specimens and the levels of fluoride release were assessed at the baseline and after 1, 2, 24, 48 and 168 h from the application with the use of an ion-specific electrode. The specimens were immersed into artificial saliva with pH adjusted to 4, 5 and 7. The highest cumulative release of fluoride was obtained by MI Varnish (11.52 ppm/mg), regardless of the pH of the environment, whereas the lowest released fluoride concentration was achieved by Embrace Varnish (4.82 ppm/mg). In the acidic environment, the release of fluoride was significantly higher than in the neutral environment for all investigated varnishes, with no change in the overall fluoride release profile and with maximum fluoride release in the first two hours after application. The findings of this study indicate that all examined fluoride varnishes released the maximum amount of fluoride within the first hours after application and that it was related to the acidity of the immersion medium.

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Section: Discussionmentioning

confidence: 99%

In Vitro Comparison of the Fluoride Ion Release from the First- and Second-Generation Fluoride Varnishes

2023

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“…20 Difluorosilane 0,9% memiliki kandungan fluoride sebanyak 0,1% atau 1.000 ppm dan kombinasi Sodium fluoride 5% dengan Tricalcium phosphate memiliki kandungan fluoride sebanyak 2,26% atau 22.600 ppm. 21 Konsentrasi fluoride dalam plak memiliki peran dalam peningkatan pH plak dan pencegahan metabolisme Streptococcus mutans dan Lactobacillus dengan cara menghambat enzim enolase yang diperlukan untuk memproduksi asam laktat. 20 Selain itu, menurut penelitian Park dkk (2011), Difluorosilane 0,9% memiliki pH yang rendah yaitu pH 2,5.…”

Section: Pembahasanunclassified

Perbandingan Difluorosilane 0,9% Dan Kombinasi Sodium Fluoride 5% Dengan Tricalcium Phosphate Terhadap Perubahan Ph Plak Dan Ph Saliva Anak

Sofrullah¹,

Dewi²,

Puspitasari³

2021

Dentin

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Background: Low water acidity (pH) in wetland area can cause caries by decreasing plaque pH and salivary pH. The usage of Difluorosilane and combination of Sodium fluoride with Tricalcium phosphate can prevent caries. Objective: to compare Difluorosilane 0.9% and combination of Sodium fluoride 5% with Tricalcium phosphate on plaque pH and salivary pH changes in children at Barito Kuala. Method: This study was true experimental with total sample were 12 people who were divided into 3 groups. Plaque and saliva samples were measured before application and 1 hour after application using a pH meter. Results: One-Way ANOVA and Post Hoc Bonferroni test results indicated that there is significant differences(p<0,05) in plaque pH and salivary pH changes between Difluorosilane 0.9% group, combination of Sodium fluoride 5% with Tricalcium phosphate group, and control group. Plaque pH and salivary pH changes in Difluorosilane 0.9% group is (0,03±0,088) and (0,01±0,063), combination of Sodium fluoride 5% with Tricalcium phosphate group is (0,16±0,044) and (0,09±0,060), control group is (-0,09±0,021) and (-0,10±0,029). Conclusion: Combination of Sodium fluoride 5% with Tricalcium phosphate can increase plaque pH and salivary pH greater than Difluorosilane 0.9% for children aged 7-9 years at Barito Kuala.Keywords: Difluorosilane, Plaque pH, Salivary pH, Sodium fluoride, Tricalcium phosphate, wetlandABSTRAKLatar belakang: Penggunaan air dengan pH yang rendah pada lahan basah dapat menyebabkan karies melalui penurunan pH plak dan pH saliva. Pencegahan karies dapat dilakukan dengan penggunaan Difluorosilane dan kombinasi Sodium fluoride dengan Tricalcium phosphate. Tujuan: membandingkan Difluorosilane 0,9% dan kombinasi Sodium fluoride 5% dengan Tricalcium phosphate terhadap perubahan pH plak dan pH saliva pada anak di Kabupaten Barito Kuala. Metode: Penelitian ini menggunakan metode penelitian True Eksperimental dengan sampel sebanyak 12 orang yang dibagi menjadi 3 kelompok. Sampel plak dan saliva dilakukan pengukuran menggunakan pH meter pada saat sebelum aplikasi dan 1 jam setelah aplikasi. Hasil: Hasil uji One-Way ANOVA dan Post Hoc Bonferroni menyatakan terdapat perbedaan perubahan pH plak dan pH saliva yang bermakna (p<0,05) antara kelompok aplikasi Difluorosilane 0,9%, aplikasi kombinasi Sodium fluoride 5% dengan Tricalcium phosphate, dan tanpa perlakuan. Perubahan pH plak dan pH salivap pada aplikasi Difluorosilane 0,9% yaitu (0,03±0,088) dan (0,01±0,063), aplikasi kombinasi Sodium fluoride 5% dengan Tricalcium phosphate yaitu (0,16±0,044) dan (0,09±0,060), serta tanpa perlakuan yaitu (-0,09±0,021) dan (-0,10±0,029). Kesimpulan: Aplikasi kombinasi Sodium fluoride 5% dengan Tricalcium phosphate dapat meningkatan pH plak dan pH saliva lebih besar dibandingkan dengan aplikasi Difluorosilane 0,9% pada anak usia 7-9 tahun di Kabupaten Barito Kuala.Kata kunci: Difluorosilane, lahan basah, pH plak, pH saliva, Sodium fluoride, Tricalcium phosphate.

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Mineralizing agents to manage early carious lesions. Part II: clinical application

2023

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The successful commercialization of mineralization technologies used for the primary and secondary prevention of early carious lesions provides several clinical options for the oral healthcare team using the minimum intervention oral care (MIOC) delivery framework. These new technologies are available in many different forms, with different properties, and can be used in a variety of clinical scenarios. This article is the second in a series providing a review on the clinical efficacy of new technologies and the products available, as well as clinical guidance for their use. CPD/Clinical Relevance: Clinicians should have an appreciation of the different mineralizing agents available, and their related guidelines.

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Clinical Study Remineralization Effect of Mineralization Varnish

Cited by 3 publications

References 2 publications

In Vitro Comparison of the Fluoride Ion Release from the First- and Second-Generation Fluoride Varnishes

In Vitro Comparison of the Fluoride Ion Release from the First- and Second-Generation Fluoride Varnishes

Perbandingan Difluorosilane 0,9% Dan Kombinasi Sodium Fluoride 5% Dengan Tricalcium Phosphate Terhadap Perubahan Ph Plak Dan Ph Saliva Anak

Mineralizing agents to manage early carious lesions. Part II: clinical application

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