Clinical Survey of 3680 Iris Tumors Based on Patient Age at Presentation

Shields, Carol L.; Kancherla, Swarupa; Patel, Jena; Vijayvargiya, Priya; Suriano, M.M.; Kolbus, Emily; Badami, Ami; Sharma, Priya; Jacobs, Emily; Voluck, Matt; Zhang, Zina; Kansal, Rishav; Shields, Patrick W.; Bianciotto, Carlos; Shields, Jerry A.

doi:10.1016/j.ophtha.2011.07.059

Cited by 143 publications

(158 citation statements)

References 22 publications

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“…Pain was related to secondary glaucoma in case 1 and to inflammation in case 2. All cases had a history of previously treated malignancy, as did the majority of patients in previous studies (4,5) . Melanoma is considered the main differential diagnosis of iris metastasis, but it is clinically challenging to diagnose due to a lack of specific pathognomonic features (7) .…”

Section: Discussionmentioning

confidence: 72%

“…Uveal metastases occur far more frequently in the choroid than in the iris, possibly due to the substantial blood supply to the posterior choroid by the posterior ciliary arteries (3) . Metastatic tumors to the iris are relatively uncommon; they may present as stromal nodules or ill-defined iris thickening, or they may be associated with atypical features such as pain, iridocyclitis, and hyphema (4,5) . In 2014, Shields et al reported their 40-year experience of 104 cases of iris metastases arising from systemic cancer, demonstrating the breast, lung, and skin as the most common primary sites for such lesions (4) .…”

Section: Introductionmentioning

confidence: 99%

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Iris metastases from systemic cancer: a report of three cases

Mello¹,

Brasil²,

Vidoris³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Ocular metastasis is relatively uncommon, with a reported incidence of approximately 8%, according to the results of autopsy evaluation. The majority of ocular metastases are located within the choroid, while metastatic tumors affecting the iris are rare. Metastatic tumors may manifest as stromal nodules or ill-defined iris thickening, or they may present with nonspecific features such as pain, iridocyclitis, and hyphema. Here, we describe three patients with iris metastasis and discuss the diagnostic challenges and unusual findings associated with these cases.

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Section: Discussionmentioning

confidence: 72%

Section: Introductionmentioning

confidence: 99%

Iris metastases from systemic cancer: a report of three cases

Mello¹,

Brasil²,

Vidoris³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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“…(7) Of 57 reported iris vascular tumors, none were associated with Sturge-Weber syndrome or choroidal hemangiomas. 7 Conversely, there are no known reports of Sturge-Weber patients with iris hemangioma, although iris neovascularization can occur. 8 The authors propose that as in Sturge-Weber syndrome, in which a somatic mosaic mutation is thought to cause maldeveloped vascular tissue in a geographic distribution including the brain, eye and skin, the association of iris hemangioma and choroidal hemangioma results from an analogous mutation at a different point in development.…”

Section: Sector Iris Hemangioma In Association With Diffuse Choroidalmentioning

confidence: 99%

The best of the best: a review of select pediatric ophthalmology and strabismus case reports published in 2015

Kemp

2016

Digit J Ophthalmol

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This review highlights 4 case reports in the field of pediatric ophthalmology and strabismus published in the year 2015. The first article describes ocular presentations of acute childhood leukemia relapse. The second demonstrates the association of sector iris hemangioma with diffuse choroidal hemangioma. The third article provides a secondary procedure for persistent hypertropia in thyroid-related orbitopathy, and the fourth article describes a treatment for cyclic esotropia with temporary use of prismatic correction.

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“…1 Çocukluktaki iris lezyonlarının %25'ini, genç erişkinlerde % 36'sını ve orta ve ileri yaş erişkinlerdeki iris lezyonlarının %47'sini oluşturur. 2 İris nevüsleri nadiren doğuşta mevcut iken sıklıkla ergenlik sonrası belirginleşerek tanı alır (Resim 1). Çoğunlukla beyaz ırkta ve mavigözlü bireylerde, sıklıkla 5.dekatta tespit edilir.…”

Section: İris Nevüsleriunclassified

İris nevi and melanomas: Distinguishing parameters

Duman¹,

Duman²,

Doğan³

2015

Acta Oncol Tur.

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ÖZETİris melanomlarının çoğu daha önce var olan iris nevüsleri üzerinden gelişmektedir. İris melanomlarının enükleasyon, metastaz ve fonksiyonel kayba neden olma riskleri nedeniyle erken tanıları oldukça önemlidir. İris nevüsünden melanom gelişimini kestirecek klinik parametrelerin farkında olunması melanom gelişimi açısından riskli nevüs grubunun belirlenmesini ve iris melanomların erken tespitini kolaylaştıracaktır. Bu derlemede iris nevüslerinin ve melanomlarının klinik özellikleri ve ayırt edici klinik parametreler sunuldu. Böylelikle bu hastalara klinik yaklaşımda yardımcı olunması amaçlandı. Anahtar Kelimeler: iris, nevüs, melanom. ABSTRACTMost of the iris melanomas arise from pre-existing iris nevi. Early diagnosis of iris melanomas is quite important because of potential risk of enucleation, metastasis and functional loss. Being aware of the clinical parameters predicting the development of melanoma from pre-existing nevus will help determining the hazardous nevus group and early diagnosis of iris melanomas. In this review, clinical features of iris nevi and melanomas and distinguishing clinical parameters were presented. Thus, helping in the clinical management of such patients were aimed.

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Clinical Survey of 3680 Iris Tumors Based on Patient Age at Presentation

Cited by 143 publications

References 22 publications

Iris metastases from systemic cancer: a report of three cases

Iris metastases from systemic cancer: a report of three cases

The best of the best: a review of select pediatric ophthalmology and strabismus case reports published in 2015

İris nevi and melanomas: Distinguishing parameters

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