Clinico-biochemical and therapeutic studies on notoedric mange in pet rabbits

Abstract

Two male and two female pet rabbits of about 1 year of age, naturally infested with Notoedres cuniculi were studied in the present investigation. Clinical examination revealed presence of crustaceous lesions on the head, ear pinnae, both the limbs and external genitalia. Microscopic examination of skin scrapings confirmed presence of Notoedres mange infestation. Biochemical parameters revealed altered values of total serum protein, albumin, globulin, and activities of aspartate amino transferase, alanine amino transferase and alkaline phosphatase respectively. The affected rabbits were treated with two injections of Ivermectin (400 μg/kg, subcutaneously, at interval of 15 days) along with supportive therapy. This treatment showed appreciable improvement in clinical signs and restoration in biochemical parameters.

Clinicopathological diagnosis and therapeutic management of sarcoptic mange in a rabbit and cat

“…Thus, on the basis of history, clinical manifestations and evidence of parasites in skin scrapings, both the rabbit and cat were diagnosed as having Sarcoptes infection. The presence of crusts and scab lesions on the head, ears and around the face in both cases is in agreement with the findings of earlier workers (DARZI et al, 2007;MITRA et al, 2014;GALDHAR et al, 2015). The morphological characters were similar to those reported by RADI (2004).…”

Biomarkers as predictive tools to test the in vivo anti-sarcoptic mange activity of propolis in naturally infested rabbits

“…Group II included infested rabbits treated using 10% propolis ointment twice a day. Group III included infested rabbits treated with 1% ivermectin sterile solution [Jaapharm Canada Inc., Jaamectin TM] at an SC dosage of 400 µg/kg (two injections at a 2-week interval) [ 4 ]. Finally, group IV consisted of infested rabbits treated with both ivermectin and propolis ointment, as previously described.…”

“…To assess the toxic effects of propolis in the livers and kidneys of the rabbits, blood samples were taken from each rabbit’s ear vein on the 1 st , 15 th and 28 th day to obtain serum that was subsequently stored at −20°C until evaluated. Biochemical parameters such as albumin, serum total protein, globulin, AST, ALP, and ALT [ 4 ] were evaluated using commercial kits with a Reflotron® Plus system; serum cortisol levels [ 5 ] were measured using commercially available coated-tube radioimmunoassay kits. The values prior to and post-treatment were statistically assessed.…”

“…If left untreated, mange can be fatal [ 3 ]. Additionally, some biochemical and hematologic indices are also affected, including heightened albumin levels, serum total protein, AST, globulin, ALP and ALT [ 4 ], in addition to increased serum cortisol levels [ 5 ]. It is not as easy to eradicate S. scabiei in rabbits compared with other domestic animals [ 6 ].…”

Oxiurose e outras nematodeoses em coelhos de criação comercial na cidade de Viamão - RS

“…Infecções parasitárias em coelhos domésticos foram estudadas na Polônia (SADZIKOWSKI et al, 2008;SZKUCIK et al, 2014), Alemanha (HAUPT, 1975;DÜWEL, 1980;), França (AUDEBERT et al, 2003), Espanha (GOMEZ-BAUTISTA et al, 1987;TENORA et al, 2002), República Checa (PAKANDL, 2009), Itália (PAPESCHI et al, 2013), Egito (ASHMAWY et al, 2010SULTAN et al, 2015), Índia (DARZI et al, 2007GALDAHAR et al, 2015), Iraque (ALTAMEMY, 2014), China (CAI et al, 2012), União Soviética (ALICATA, 1932;YEATTS, 1994) e Nova Zelândia (RINALDI et al, 2007;SIVAJOTHI et al, 2014, conforme citado por ILIC et al, 2018.…”