Clinico pathological aspects of solitary thyroid nodule: a hospital based prospective study

Abstract

Background: Nodular goitre is a common endocrine problem in the world today. Solitary thyroid nodule is defined as the presence of a palpable nodule in the otherwise normal thyroid gland. Solitary nodules are one of the most frequent presentations of thyroid disorder. The aim of this study was to study the incidence and other clinical parameters of solitary thyroid nodules and to correlate between clinical diagnosis and histopathological examination of solitary nodule thyroid.Methods: A prospective study was done in patients with solitary thyroid swelling, after taking a detailed history, were examined clinically and confirmed with FNAC and underwent thyroid surgery were included in this study. The histopathological reports were evaluated and correlated with clinical diagnosis by standard statistical methods.Results: Majority of the patients were between 21-30 years of age. Female:male ratio was about 11.5:1. Swelling in front of the neck was the most common presentation. Most common solitary thyroid swelling was the colloid goitre. Commonest surgery performed was hemithyroidectomy.Conclusions: The majority of the solitary nodule of the thyroid was found to be benign, and this illustrates that hemithyroidectomy is the preferred surgery unless malignancy is suspected by fine needle aspiration cytology.

Clinicopathological Profile of Patient with Solitary Thyroid Nodule Presented to OPD at a Tertiary Care Hospital Pakistan

“…While the majority of our patients also fall within the middle age range (26-35 years), our study has a broader age distribution, including a smaller proportion in the 36-50 years age group (7.2%) and a limited representation of patients over 50 years old (4%). 13 Additionally, the gender distribution in our study shows a reverse trend with 42.4% females and 57.6% males, differing from the female preponderance reported by Rajendranet al (2018) and enkatachalapathyTSetal. 14 Similar to our results, Edwin et al (2020) reported swelling as the predominant symptom in their study, with 50% of patients presenting with this manifestation.…”

“…Moreover, previous study has linked thyroid hormones to indicators of an adverse metabolic profile, even when they are within the normal range. 12 In comparison to Rajendran et al (2018), our study demonstrates a slightly higher mean age of patients at 48.7 years (SD = 2.11). While the majority of our patients also fall within the middle age range (26-35 years), our study has a broader age distribution, including a smaller proportion in the 36-50 years age group (7.2%) and a limited representation of patients over 50 years old (4%).…”

Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule

“…There is no inadequate or insufficient cytological smear while a study by Rajendran et al, in 2018 39 observed majority of FNAC reported colloid goiter (84%), 14% showed papillary carcinoma followed by follicular neoplasm (2%).…”

Study of clinical profile of solitary thyroid nodule and its management

“…In our study similar to all other studies it is evident that commonest FNAC result is a benign lesion. [12] Present Series Hemithyroidectomy 72 93.3 Subtotal thyroidectomy 14 Total thyroidectomy 14 6.67…”

“…Adenomatous goiter are in higher incidences when there is iodine deficient diet. [4] 1980 12 Gary [10] 1972 28.7 Gharib [8] 1984 24 Nagori et al [6] 1992 11 Anantha Krishnan [7] 1993 15.3 Osman Uyar [6] 2017 36.9 S. Rajendran [12] 2018 10 Present Series 2020 10…”