CNS activity of Calotropis gigantea roots

Argal, Ameeta; Pathak, Anupam

doi:10.1016/j.jep.2005.12.024

Cited by 99 publications

(67 citation statements)

References 11 publications

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“…28 Phytochemicals which constitute the non-nutritive components of plants protect the plant against pests and diseases and they also help to protect humans against variety of diseases. 15,29 Turmeric has also been reported to be an anti-diabetic. 30 It is claimed that it reduces the risk of diabetic by lowering the level of glucose-6-phosphate and raises the action of liver.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Evaluation, Phytochemical Screening and Ascorbic Acid Assay of Turmeric (Curcuma longa)

Oghenejobo¹

2017

MOJBB

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The ethanolic extract of Turmeric (Curcuma longa) was subjected to microbial susceptibility test using the agar well diffusion method. The extract was found to be active against the bacteria used as it inhibited all the organisms with the highest inhibition zone of 13.7mm recorded against Shigella flexnerri and the least inhibition of 2.3mm recorded against Staphylococcus epidermis. Minimum Inhibitory Concentration (MIC) values range from 6.25mg/ml to 200mg/ml. Shigella flexnerri gave MIC of 6.25mg/ml, S. aureus and K. Pneumonia, 25mg/ml, E. coli, 50mg/ml, S. epidermis, Lactobacillus and P. aeruginosa, 100mg/ml and V. cholera and S. typhi 200mg/ml respectively. Secondary metabolites were also screened using phytochemistry. Fourteen (14) secondary metabolites were screened from the ethanolic extract. The presence of these phytochemicals like tannins, alkaloids, phenols, steroids, flavonoids, phlobatannin, cardiac glycosides, terpenoids, triterpenes, saponin, etc; is indicative of the antimicrobial activity of Turmeric. The extract was found to contain 66.749mg/100ml ascorbic acid which is relatively comparable to many fruits recommended by dieticians. The value of curcumin present (Rf value 0.436) is also relatively close to that of pure curcumin. The results so far obtained are indicative of the good medicinal value of Turmeric in both pharmaceutical and pharmacological formulations.

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Section: Discussionmentioning

confidence: 99%

Antibacterial Evaluation, Phytochemical Screening and Ascorbic Acid Assay of Turmeric (Curcuma longa)

Oghenejobo¹

2017

MOJBB

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“…Plants contain lot of phytochemicals like alkaloids, tannins, flavonoids, amino acids, saponins, terpenes, fatty acids, glycosides and sterols that have disease preventive properties [17,18]. It is already reported that steroids, triterpenoids and saponins have the analgesic properties and central nervous system activities [19,20]. Reports show that saponins possess hypocholesterolemic, antiinflammatory, antidiabetic properties, hemolytic and foaming activity, antifungal, fungistatic and molluscidal activity [21].…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Evaluation of Various Solvent Extracts of the Leaves, Fruits and Shoots of Ferula Jaeschkeana Vatke

Yaqoob¹,

Nawchoo²,

Ahmad³

2016

Herb Med

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The genus Ferula possess strong aromatic smell due to the presence of essential oil or oleoresin and is well-known in folk medicine for the treatment of various disorders. The present study aimed to investigate the presence of phytochemicals in various solvent extracts of leaves, fruits and shoots of Ferula jaeschkeana Vatke. This study investigates the effects of ethanol, methanol, chloroform, petroleum ether and aqueous extracts of leaves, fruits and shoots. Phytochemical screening revealed the presence of various phytochemical constituents in the extracts of leaves, fruits and shoots. Phytochemical analysis of extracts of leaves confirmed the presence of flavonoids, alkaloids, terpenoids, saponins, phenolic compounds, proteins, anthraquinone glycosides, phytosterols, tannins, steroids, coumarins, quinones, carbohydrates, resins, triterpenoids and xanthoproteins, while it gave the negative results for cardiac glycosides, amino acids, phlobotannins and oxalates. Phytochemical analysis of extracts of fruits revealed the presence of all phytochemicals except anthraquinone glycosides, phlobotannins and xanthoproteins. Phytochemical analysis of extracts of shoots confirmed the presence of all phytochemicals except phlobotannins and oxalates. The presence of a several phytochemicals in Ferula jaeschkeana Vatke may serve as a possible source for the development of plant based novel drugs.

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“…Steroids and triterpenoids show the analgesic properties. The Steroids and saponins were responsible for central nervous system activities [13] , flavonoids have been referred to as nature's biological response modifiers, because of their inherent ability to modify the body's reaction to allergies and virus and they showed their anti-allergic, anti-inflammatory, anti-microbial and anti-cancer activities [14] .…”

Section: A Qualitative Phytochemical Analysismentioning

confidence: 99%

Qualitative and Quantitative Phytochemical Analysis of Simarouba Glauca Leaf Extract.

Gurupriya¹

2017

IJRASET

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CNS activity of Calotropis gigantea roots

Cited by 99 publications

References 11 publications

Antibacterial Evaluation, Phytochemical Screening and Ascorbic Acid Assay of Turmeric (Curcuma longa)

Antibacterial Evaluation, Phytochemical Screening and Ascorbic Acid Assay of Turmeric (Curcuma longa)

Phytochemical Evaluation of Various Solvent Extracts of the Leaves, Fruits and Shoots of Ferula Jaeschkeana Vatke

Qualitative and Quantitative Phytochemical Analysis of Simarouba Glauca Leaf Extract.

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