Coating of Dacron vascular grafts with an ionic polyurethane: a novel sealant with protein binding properties

Phaneuf, Matthew D.; Dempsey, Donald J.; Bide, Martin; Quist, William C.; LoGerfo, Frank W.

doi:10.1016/s0142-9612(00)00202-7

Cited by 44 publications

(31 citation statements)

References 19 publications

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“…Until 10 years ago, approximately 90% of prostheses in large animal models were as short as 5.571.2 cm (Dacron and expended polytetrafluoroethylene (ePTFE)) and 4.571.7 cm polyurethanes (PU), with a median implantation periods of 91.8717.3 days for Dacron grafts, 60.079.36 days for polytetrafluoroethylene (PTFE) grafts [11] and 907127.1 days for PU grafts. In more recent years, slightly longer grafts were implanted (64% were still shorter than 7 cm) and observation periods became shorter (medians: 28.078.9 and 14.0718.7 for ePTFE and Dacron, respectively) [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29]. In the small proportion of studies where truly long prostheses were implanted, they were either aorto-aortic [30][31][32][33][34][35], aorto-iliac [36][37][38][39] or aorto-femoral [40].…”

Section: Transanastomotic Endothelialization (Tae): Barking Up the Wrmentioning

confidence: 99%

Prosthetic vascular grafts: Wrong models, wrong questions and no healing

2007

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Section: Transanastomotic Endothelialization (Tae): Barking Up the Wrmentioning

confidence: 99%

Prosthetic vascular grafts: Wrong models, wrong questions and no healing

2007

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“…27,28 The devices were hydrated for 30 min and completely crushed five times to simulate extensive manipulations. They were then cannulated with surgical sutures on semirigid silastic tubes at both sides.…”

Section: Swelling Behaviormentioning

confidence: 99%

Biodegradable membrane‐covered stent from chitosan‐based polymers

Thierry

Merhi

Silver³

et al. 2005

J Biomedical Materials Res

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Membrane-covered devices could help treat disease of the vasculature such as aneurysm, rupture, and fistulas. They are also investigated to reduce embolic complication associated with revascularization of saphenous vein graft. The aim of this study is to design a clinically applicable biodegradable membrane-covered stent based on the natural polysaccharide chitosan, which has been developed. The mechanical properties of the membrane is optimized through blending with polyethylene oxide (70:30% Wt CH:PEO). The membrane was able to sustain the mechanical deformation of the supporting self-expandable metallic stents during its deployment. The membrane was demonstrated to resist physiological transmural pressure (burst pressure resistance >500 mm Hg) and presented a high-water permeation resistance (1 mL/cm(2) min(-1) at 120 mmHg). The CH-PEO membrane showed a good hemocompatibility in an ex vivo assay. Heparin and hyaluronan surface complexation with the membrane further reduced platelet adhesion by 50.1 and 63% (p = 0.05). The ability of the membrane-covered devices to be used as a drug reservoir was investigated using the nitric oxide donor sodium nitroprusside (SNP). SNP-loaded membranes displayed significantly reduced platelet adhesion.

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“…The porosity of commercially available polyester (Dacron) knitted vascular grafts can be reduced by coating or sealing with a novel ionic urethane, to improve their blood-proof property. The mechanical properties of coated vascular grafts have been found to be comparable with, or superior to, the pre-coated Dacron substrate [23][24][25][26][27][28][29][30][31][32][33].…”

Section: Introductionmentioning

confidence: 93%

Small diameter Polyurethane vascular graft reinforced by elastic weft-knitted tubular fabric of polyester/spandex

Zhou

Ouyang

et al. 2008

Fibers Polym

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Small diameter vascular grafts were fabricated from pure Polyurethane (PU) as well as PU reinforced with a tubular weft-knitted fabric. The tensile properties of the reinforced composite vascular grafts were compared with that of the tubular fabric itself and the pure PU vascular grafts. The elasticity and strength of the reinforced vascular grafts were improved compared with the tubular fabric. Strength of the reinforced vascular grafts was 5-10 times of the strength of the pure PU vascular grafts. Expanding the tubular fabric to increase the inner diameter of the reinforced vascular graft reduced the graft's strength and initial modulus, but the difference was reduced as the PU content was increased. For grafts of the same inner diameter, increasing the PU content increased the thickness and strength of the graft wall, which led to a general increase in the strength and initial modulus of the composite vascular grafts.

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Coating of Dacron vascular grafts with an ionic polyurethane: a novel sealant with protein binding properties

Cited by 44 publications

References 19 publications

Prosthetic vascular grafts: Wrong models, wrong questions and no healing

Prosthetic vascular grafts: Wrong models, wrong questions and no healing

Biodegradable membrane‐covered stent from chitosan‐based polymers

Small diameter Polyurethane vascular graft reinforced by elastic weft-knitted tubular fabric of polyester/spandex

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